Dipalmitoyl hydroxyproline
Description
Dipalmitoyl hydroxyproline (CAS 41672-81-5), also known commercially as LIPACIDE DPHP, is a lipophilic derivative of hydroxyproline used in personal care formulations.
It combines a fatty acid component with an amino acid to deliver moisturizing and stabilizing activity within oil-based systems. Formulators source it primarily as a skin-conditioning active.
In facial and body care emulsions, it functions as a humectant that supports moisture retention within the lipid phase of the formulation. It is incorporated into anti-aging creams and serums.
Its antioxidant properties help protect formulation integrity and support skin barrier function. Hair care products such as conditioning treatments use it to deliver amino acid-derived benefits.
Its lipophilic character also suits it for anhydrous formats including balms, sticks, and oil serums where water-soluble actives cannot be used effectively in the manufacturing process.
Dipalmitoyl hydroxyproline is typically supplied as a waxy solid or powder suitable for incorporation into the oil phase of cosmetic formulations. It is available in cosmetic-grade specification.
This is the standard for personal care raw material procurement. Packaging is commonly offered in kilogram quantities for development-scale sourcing through to larger bulk formats for production.
Physical Properties
| Boiling Point | 696.6±55.0 °C(Predicted) |
| Density | 0.98±0.1 g/cm3(Predicted) |
| Water Solubility | 1mg/L at 20℃ |
| Vapor Pressure | 0Pa at 25℃ |
| Log P | 7 |
Safety & Handling (Learn More)
Documentation
Other Names
trans-O, N-Dipalmitoylhydroxyproline|E6AHA53N1H|LIPACIDE DPHP|SEPILIFT DPHP|RONACARE ASC III|L-Proline, 1-(1-oxohexadecyl)-4-[(1-oxohexadecyl)oxy]-, (4R)-|L-Proline, 1-(1-oxohexadecyl)-4-[(1-oxohexadecyl)oxy]-, trans-|(4R)-1-(1-Oxohexadecyl)-4-[(1-oxohexadecyl)oxy]-L-proline
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