L-hydroxyproline
Description
L-Hydroxyproline (CAS 51-35-4), commonly abbreviated as Hyp, is a non-essential amino acid derived primarily from collagen hydrolysis. It functions as a biochemical marker for collagen content and serves as a building block in peptide synthesis.
In pharmaceutical manufacturing, Hyp is used as a reference standard and synthetic intermediate in the production of collagen-related peptides and drug compounds targeting connective tissue. It is essential for nutraceutical formulations and cosmetic actives development.
Food and nutrition manufacturers incorporate it into collagen-based supplements, functional protein blends, and hydrolyzed collagen products where amino acid profile verification is required. This ensures high-quality standards for consumer health products.
Personal care formulators use it as a moisturizing and stabilizing agent in anti-aging creams, serums, and skin-conditioning treatments where collagen support claims are commercially relevant. It helps maintain the structural integrity of topical applications.
It also serves as an analytical reagent in quality control laboratories for quantifying collagen content in raw materials and finished products. This application is vital for maintaining consistency across various industrial manufacturing processes.
L-Hydroxyproline is supplied as a white crystalline powder. It is available in USP, FCC, and reagent-grade specifications to meet the sourcing requirements of pharmaceutical, food, and cosmetic manufacturers.
Bulk quantities are standard for industrial buyers, with smaller quantities available for R&D and QC applications. Our supply chain ensures that all technical requirements and quality benchmarks are met for every shipment.
Physical Properties
| Melting Point | 274 °C |
| Boiling Point | 242.42°C (rough estimate) |
| Density | 1.478 g/cm³ |
| Appearance | White crystalline powder |
| Color | White |
| Odor | Odorless |
| Form | Crystals or Crystalline Powder |
| Water Solubility | 357.8 g/L (20 º C) |
| Refractive Index | -75.5 ° (C=4, H2O) |
| pH | 5.5-6.5 (50g/l, H2O, 20℃) |
| Log P | -0.350 (est) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29339990 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
trans-L-Hydroxyproline|trans-Hydroxyproline|trans-4-Hydroxyproline|LS-hydroxyproline|L-4-Hydroxyproline|Hypro|Hyp|Hydroxy-proline
Related Products
Need a chemical? Get a quote within 24 hours.