Oxaceprol

CAS Number
33996-33-7
EC Number
251-780-6
Chemical Formula
C7H11NO4
Molecular Weight
173.17 g/mol

Description

Oxaceprol (CAS 33996-33-7), also known by the trade name Jonctum and commercially as acetyl hydroxyproline, is a modified amino acid derivative used in pharmaceutical and cosmetic formulations. It functions as a humectant, antioxidant stabilizer, and pH-buffering agent, supporting both skin conditioning and active ingredient performance in finished products for various industries.

In pharmaceutical preparations, it has been developed as an active ingredient in anti-inflammatory and joint-support formulations, particularly for oral and topical dosage forms targeting connective tissue. Cosmetic formulators incorporate it into premium skincare products, such as serums, creams, and masks, where its moisture-retention capacity supports essential skin hydration claims.

Its buffering behavior helps stabilize pH-sensitive formulations, making it relevant for developers working with peptide-based or enzyme-active systems in modern laboratory settings. The compound also appears in functional topical preparations where collagen-pathway support is a desired positioning attribute for high-end personal care and dermatological brands.

This material is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications suited to drug product manufacturing and cosmetic-grade material. Buyers should confirm purity levels and documentation, including COA and relevant pharmacopoeial alignment, when sourcing for regulated end uses in global chemical markets.

Other Names (Synonyms)

(2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid|Jonctum|acetyl hydroxyproline|N-Acetylhydroxyproline|Q0XV76B96L|(-)-1-Acetyl-4-hydroxy-L-proline|L-Proline, 1-acetyl-4-hydroxy-, (4R)-|L-Proline, 1-acetyl-4-hydroxy-, trans-

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 132 °C
Boiling Point 303.8°C (rough estimate)
Density 1.3346 (rough estimate)
Color White
Form Crystalline Powder
Vapor Pressure 0Pa at 20℃
Refractive Index 1.4490 (estimate)
Log P -1.51 at 20℃

Documentation

Safety & Handling Learn More

Danger
GHS05· Corrosive GHS07· Irritant

Hazard Statements

H315 H315
H318 H318
H335 H335

Precautionary Statements

P261 P261
P264 P264
P271 P271
P280 P280

Trade & Regulatory

HS Code 29339900
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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