SoleChem

Oxaceprol

Amino Acids & Peptides Personal Care & Cosmetics
CAS
33996-33-7
EC
251-780-6
Mol. Weight
173.17 g/mol

Description

Oxaceprol (CAS 33996-33-7), also known by the trade name Jonctum and commercially as acetyl hydroxyproline, is a modified amino acid derivative used in pharmaceutical and cosmetic formulations.

It functions as a humectant, antioxidant stabilizer, and pH-buffering agent, supporting both skin conditioning and active ingredient performance in finished products for various industries.

In pharmaceutical preparations, it has been developed as an active ingredient in anti-inflammatory and joint-support formulations, particularly for oral and topical dosage forms targeting connective tissue.

Cosmetic formulators incorporate it into premium skincare products, such as serums, creams, and masks, where its moisture-retention capacity supports essential skin hydration claims.

Its buffering behavior helps stabilize pH-sensitive formulations, making it relevant for developers working with peptide-based or enzyme-active systems in modern laboratory settings.

The compound also appears in functional topical preparations where collagen-pathway support is a desired positioning attribute for high-end personal care and dermatological brands.

This material is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications suited to drug product manufacturing and cosmetic-grade material.

Buyers should confirm purity levels and documentation, including COA and relevant pharmacopoeial alignment, when sourcing for regulated end uses in global chemical markets.

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Physical Properties

Melting Point 132 °C
Boiling Point 303.8°C (rough estimate)
Density 1.3346 (rough estimate)
Color White
Form Crystalline Powder
Vapor Pressure 0Pa at 20℃
Refractive Index 1.4490 (estimate)
Log P -1.51 at 20℃

Safety & Handling (Learn More)

Danger GHS05 GHS07
Hazard Statements
H315 H315
H318 H318
H335 H335
Precautionary Statements
P261 P261
P264 P264
P271 P271
P280 P280
P317 P317
P319 P319
P321 P321
P405 P405
P501 P501
P264+P265 P264+P265
P302+P352 P302+P352
P304+P340 P304+P340
P332+P317 P332+P317
P362+P364 P362+P364
P403+P233 P403+P233
P305+P354+P338 P305+P354+P338

Trade & Regulatory

HS Code 29339900
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

(2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid|Jonctum|acetyl hydroxyproline|N-Acetylhydroxyproline|Q0XV76B96L|(-)-1-Acetyl-4-hydroxy-L-proline|L-Proline, 1-acetyl-4-hydroxy-, (4R)-|L-Proline, 1-acetyl-4-hydroxy-, trans-

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