Oxaceprol
Description
Oxaceprol (CAS 33996-33-7), also known by the trade name Jonctum and commercially as acetyl hydroxyproline, is a modified amino acid derivative used in pharmaceutical and cosmetic formulations.
It functions as a humectant, antioxidant stabilizer, and pH-buffering agent, supporting both skin conditioning and active ingredient performance in finished products for various industries.
In pharmaceutical preparations, it has been developed as an active ingredient in anti-inflammatory and joint-support formulations, particularly for oral and topical dosage forms targeting connective tissue.
Cosmetic formulators incorporate it into premium skincare products, such as serums, creams, and masks, where its moisture-retention capacity supports essential skin hydration claims.
Its buffering behavior helps stabilize pH-sensitive formulations, making it relevant for developers working with peptide-based or enzyme-active systems in modern laboratory settings.
The compound also appears in functional topical preparations where collagen-pathway support is a desired positioning attribute for high-end personal care and dermatological brands.
This material is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications suited to drug product manufacturing and cosmetic-grade material.
Buyers should confirm purity levels and documentation, including COA and relevant pharmacopoeial alignment, when sourcing for regulated end uses in global chemical markets.
Physical Properties
| Melting Point | 132 °C |
| Boiling Point | 303.8°C (rough estimate) |
| Density | 1.3346 (rough estimate) |
| Color | White |
| Form | Crystalline Powder |
| Vapor Pressure | 0Pa at 20℃ |
| Refractive Index | 1.4490 (estimate) |
| Log P | -1.51 at 20℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
(2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid|Jonctum|acetyl hydroxyproline|N-Acetylhydroxyproline|Q0XV76B96L|(-)-1-Acetyl-4-hydroxy-L-proline|L-Proline, 1-acetyl-4-hydroxy-, (4R)-|L-Proline, 1-acetyl-4-hydroxy-, trans-
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