L-proline

CAS Number
147-85-3
EC Number
205-702-2
FEMA Number
FEMA 3319

What is L-proline?

L-Proline (CAS 147-85-3) is a naturally occurring amino acid used commercially as a flavoring agent and humectant in food and personal care manufacturing. FEMA 3319.

Where is L-proline used?

  • Food: flavor contributor in processed and fermented systems
  • Bakery, confectionery and savory formulations: controlled browning and taste development via Maillard reactions
  • Fermented beverages and dairy: flavor profile depth in beer, wine and aged cheeses
  • Personal care: humectant in skin-conditioning moisturizers and serums
  • Hair care: water-binding capacity supports texture and hydration
  • Nutraceutical and dietary supplement producers source it as an active ingredient in amino acid blends targeting collagen synthesis support.

Good to know: Food-grade and USP/Ph. Eur. grades are the most commercially prevalent; food-grade material meets FCC specifications for flavoring and nutritional applications.

Commercial specifications

  • Bulk quantities for industrial formulators; smaller packaging for specialty and nutraceutical manufacturers

Other Names (Synonyms)

Prolinum|Proline|Prolina|L-α-pyrrolidinecarboxylic acid|L-Prolin|L-alpha-pyrrolidinecarboxylic acid|2-Pyrrolidinecarboxylic acid|(S)-Pyrrolidine-2-carboxylic acid

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What are the physical properties of L-proline?

Melting Point 220-222 °C (decomp)
Boiling Point 252.2 °C @ Press: 760 Torr
Density 1.350 g/cm³
Appearance White crystalline powder
Color White
Odor at 100.00 %. odorless
Form powder
Water Solubility soluble
Vapor Pressure 0Pa at 25℃
Refractive Index -85 ° (C=4, H2O)
pH 6.0-7.0 (25℃, 1M in H2O)
Log P -2.54 at 20℃

Which trade and regulatory codes apply to L-proline?

HS Code 29339990
Storage Class 13 - Non Combustible Solids
WGK (Germany) 3
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