L-serine
Description
L-Serine (CAS 56-45-1) is a non-essential amino acid used across food, pharmaceutical, and cosmetic manufacturing as a functional ingredient and formulation component. Commercially recognized under designations such as L-Ser and Serinum, it supports moisture retention, buffering, and stability.
In nutraceutical and dietary supplement manufacturing, it is incorporated into amino acid blends, protein fortification systems, and cognitive health formulations. Pharmaceutical manufacturers use it as a precursor and stabilizing excipient in injectable solutions and infusion fluids.
Cosmetic formulators rely on it as a humectant in skin-conditioning serums, moisturizing creams, and leave-on treatments where it supports water binding in the formulation matrix. Food producers apply it for pH buffering and antioxidant stabilization in functional food and beverage products.
This ingredient is supplied as a white crystalline powder. Standard grades include USP, Ph.Eur., and food-grade (FCC), with pharmaceutical-grade material subject to stricter purity and residue specifications.
Bulk quantities are available for industrial formulation, with smaller quantities offered for R&D and quality assurance purposes. It is also available in compliance with BP, EP, and ACS standards depending on the specific application requirements.
The material is highly soluble in water and exhibits excellent stability under standard processing conditions. This makes it a versatile choice for manufacturers looking to enhance the nutritional profile or physical properties of their chemical formulations.
Physical Properties
| Melting Point | 228 °C (decomp) |
| Boiling Point | 197.09°C (rough estimate) |
| Density | 1.6 g/cm³ @ Temp: 22 °C |
| Flash Point | 150°C |
| Appearance | White crystalline powder |
| Color | White |
| Odor | wh. cryst. or cryst. powd., odorless, sweet taste |
| Form | powder |
| Water Solubility | 250 g/L (20 ºC) |
| Refractive Index | 1.4368 (estimate) |
| pH | 5-6 (100g/l, H2O, 20℃) |
| Log P | -1.580 |
Trade & Regulatory
| HS Code | 29225000 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
Serinum|L-Serin|L-Ser|L-3-Hydroxy-alanine|L-3-Hydroxy-2-aminopropionic acid|L-3-Hydroxy-2-aminopropionate|L-2-Amino-3-hydroxypropionic acid|beta-Hydroxyalanine
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