L-arginine
Description
L-Arginine (CAS 74-79-3), commonly abbreviated as L-Arg, is a conditionally essential amino acid sourced for use across pharmaceutical, nutritional, and cosmetic manufacturing.
It functions as a pH buffer, stabilizer, and bioavailable nitrogen source in a broad range of formulated products. In pharmaceutical manufacturing, it is used to solubilize poorly water-soluble active ingredients.
It also stabilizes protein-based drug formulations, including injectables and biologics. Sports nutrition and dietary supplement producers incorporate it into pre-workout powders, capsules, and functional beverages.
Food manufacturers apply it as a flavor precursor — FEMA 3819 — in processed and heat-treated products where controlled Maillard reaction development is required for the final product.
In personal care formulations, it acts as a pH adjuster and humectant in skin creams, hair conditioners, and scalp treatments, where its buffering capacity helps maintain formula stability.
L-Arginine is supplied as a white crystalline powder in both free base and hydrochloride salt forms. Standard grades include USP, BP, Ph. Eur., and food-grade (FCC).
The hydrochloride form is commonly preferred for pharmaceutical applications requiring precise pH control. Bulk supply is available in kilogram and metric ton quantities to meet industrial production requirements.
Physical Properties
| Melting Point | 244 °C |
| Boiling Point | 367.6 °C @ Press: 760 Torr |
| Density | 1.325 g/cm³ (solid) |
| Appearance | White crystalline powder |
| Color | white |
| Odor | Faint |
| Form | powder |
| Water Solubility | 148.7 g/L (20 ºC) |
| Refractive Index | 27 ° (C=8, 6mol/L HCl) |
| pH | 10.5-12.0 (25℃, 0.5M in H2O) |
| Log P | -4.20 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29252000 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
N5-(aminoiminomethyl)-L-Ornithine|L-Arginin|L-Arg|L-alpha-Amino-delta-guanidinovaleric acid|L-alpha-Amino-delta-guanidinovalerate|L-a-Amino-D-guanidinovaleric acid|L-a-Amino-D-guanidinovalerate|5-[(Aminoiminomethyl)amino]-L-Norvaline
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