SoleChem

L-arginine

Vitamins & Nutrients Pharmaceuticals & Healthcare
CAS
74-79-3
EC
200-811-1
Mol. Weight
174.20 g/mol

Description

L-Arginine (CAS 74-79-3), commonly abbreviated as L-Arg, is a conditionally essential amino acid sourced for use across pharmaceutical, nutritional, and cosmetic manufacturing.

It functions as a pH buffer, stabilizer, and bioavailable nitrogen source in a broad range of formulated products. In pharmaceutical manufacturing, it is used to solubilize poorly water-soluble active ingredients.

It also stabilizes protein-based drug formulations, including injectables and biologics. Sports nutrition and dietary supplement producers incorporate it into pre-workout powders, capsules, and functional beverages.

Food manufacturers apply it as a flavor precursor — FEMA 3819 — in processed and heat-treated products where controlled Maillard reaction development is required for the final product.

In personal care formulations, it acts as a pH adjuster and humectant in skin creams, hair conditioners, and scalp treatments, where its buffering capacity helps maintain formula stability.

L-Arginine is supplied as a white crystalline powder in both free base and hydrochloride salt forms. Standard grades include USP, BP, Ph. Eur., and food-grade (FCC).

The hydrochloride form is commonly preferred for pharmaceutical applications requiring precise pH control. Bulk supply is available in kilogram and metric ton quantities to meet industrial production requirements.

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Physical Properties

Melting Point 244 °C
Boiling Point 367.6 °C @ Press: 760 Torr
Density 1.325 g/cm³ (solid)
Appearance White crystalline powder
Color white
Odor Faint
Form powder
Water Solubility 148.7 g/L (20 ºC)
Refractive Index 27 ° (C=8, 6mol/L HCl)
pH 10.5-12.0 (25℃, 0.5M in H2O)
Log P -4.20

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H319 Causes serious eye irritation
Precautionary Statements
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265 Wash … thoroughly after handling.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29252000
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

N5-(aminoiminomethyl)-L-Ornithine|L-Arginin|L-Arg|L-alpha-Amino-delta-guanidinovaleric acid|L-alpha-Amino-delta-guanidinovalerate|L-a-Amino-D-guanidinovaleric acid|L-a-Amino-D-guanidinovalerate|5-[(Aminoiminomethyl)amino]-L-Norvaline

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