L-citrulline
Description
L-Citrulline (CAS 372-75-8) is a non-essential amino acid naturally occurring in watermelon and produced endogenously in the urea cycle. In commercial applications, it functions as a precursor to L-arginine.
It supports nitric oxide pathway activity that underpins its use across sports nutrition, pharmaceutical, and personal care formulations. In sports nutrition, it is a primary active ingredient in pre-workout powders.
These capsules target exercise performance and muscle recovery. Pharmaceutical manufacturers use it as an active or supporting ingredient in formulations addressing urea cycle disorders and cardiovascular-related indications.
In functional food and beverage development, it is incorporated into fortified drinks and nutritional bars where amino acid enrichment is a label claim. Personal care formulators include it in topical products.
It is used for its moisture-retention contribution and its role in supporting skin barrier function. This product is supplied as a white crystalline powder for various industrial and commercial applications.
Food-grade and USP-grade specifications are the most commonly traded forms. Food-grade material meets FCC standards for use in ingestible products and dietary supplement manufacturing.
Bulk quantities are available for industrial formulation. Pharmaceutical-grade material is subject to tighter purity and testing requirements to ensure compliance with global regulatory standards for safety.
Physical Properties
| Melting Point | 235.5 °C |
| Boiling Point | 306.48°C (rough estimate) |
| Density | 1.384 g/cm³ (solid) |
| Appearance | White powder |
| Color | White |
| Odor | Odorless |
| Form | Crystals or Crystalline Powder |
| Water Solubility | 200 g/L (20 ºC) |
| Refractive Index | 26 ° (C=8, 6mol/L HCl) |
| Log P | -3.190 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29241900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
δ-ureidonorvaline|α-amino-δ-ureidovaleric acid|N5-carbamoylornithine|N5-Carbamoyl-L-ornithine|N5-(Aminocarbonyl)ornithine|N(delta)-Carbamylornithine|N(5)-(Aminocarbonyl)-L-ornithine|L-2-Amino-5-ureidovaleric acid
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