Citicoline

Citicoline (CAS 987-78-0), also known as CDP-choline, is a naturally occurring nucleotide compound used as an active ingredient in pharmaceutical formulations and functional health products. It supplies both choline and cytidine precursors in a single molecule.

This unique structure makes it a preferred raw material where combined bioavailability is a formulation requirement. In pharmaceutical manufacturing, it is the active substance in oral and injectable preparations targeting cognitive and neurological support.

Nutraceutical and dietary supplement producers incorporate it into capsules, sachets, and functional beverages. This is particularly common where choline-source labeling and documented bioavailability are key purchasing criteria for the end consumer.

Cosmetic formulators use it in premium skincare products as a humectant and membrane-supporting active. It is frequently found in anti-aging and barrier-repair formulations due to its specific biochemical properties and skin compatibility.

Biotechnology and life science suppliers also source it as a reference standard or biochemical reagent. It is widely used for cell culture and metabolic research applications where high-purity chemical precursors are necessary for study.

The material is supplied as a white to off-white hygroscopic powder, typically as the sodium salt form. This specific form offers improved stability for solid dosage manufacturing and long-term storage in industrial environments.

Standard grades include USP, BP, and Ph.Eur. to meet pharmaceutical procurement requirements. Food-grade and nutraceutical-grade material is also available for supplement applications where regulatory compliance is a prerequisite.