Citicoline

CAS Number
987-78-0
EC Number
213-580-7
Abbreviation
CDP-choline

What is Citicoline?

Citicoline (CAS 987-78-0), also known as CDP-choline, is a naturally occurring nucleotide compound used as an active ingredient in pharmaceutical formulations and functional health products.

Where is Citicoline used?

  • Pharmaceutical manufacturing: active substance in oral and injectable preparations targeting cognitive and neurological support
  • Nutraceutical and dietary supplement producers: capsules, sachets, and functional beverages
  • Cosmetic formulators: humectant and membrane-supporting active in premium skincare
  • Biotechnology and life science suppliers: reference standard or biochemical reagent
  • It supplies both choline and cytidine precursors in a single molecule.

Good to know: Standard grades include USP, BP, and Ph. Eur. to meet pharmaceutical procurement requirements.

Commercial specifications

  • Sodium salt form offers improved stability for solid dosage manufacturing and long-term storage

Other Names (Synonyms)

cytidine 5'-diphosphocholine|CDP-choline (neutral charge)|5'-O-[hydroxy({[2-(trimethylammonio)ethoxy]phosphinato}oxy)phosphoryl]cytidine|CDP-choline|cytidine diphosphate choline|Nicholin|CDP-colina|Cytidine 5′-diphosphate choline

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What are the physical properties of Citicoline?

Melting Point >185°C (dec.)
Color White
Form Solid
Log P -7.070 (est)

How is Citicoline classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 H315
H319 H319
H335 H335

Precautionary Statements

P261 P261
P264 P264
P271 P271
P280 P280
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