SoleChem

Creatine

Pharmaceutical Intermediates Pharmaceuticals & Healthcare
CAS
57-00-1
EC
200-306-6
Mol. Weight
131.13 g/mol

Description

Creatine (CAS 57-00-1) is a naturally occurring amino acid derivative used across sports nutrition, pharmaceutical, and cosmetic manufacturing. Commercially supplied as the monohydrate form, it functions as an energy-metabolism compound.

In nutritional products, it serves as a bioactive ingredient in topical formulations. In sports and clinical nutrition, it is the active ingredient in performance supplements targeting muscle energy replenishment.

Supplied in powders, capsules, and ready-to-mix formats, it is a staple for athletes. Pharmaceutical manufacturers use it as an intermediate or active compound in formulations addressing neuromuscular conditions.

Consistent purity and documented sourcing are procurement priorities for these industries. In cosmetic formulations, it is incorporated into anti-aging and skin-conditioning products for moisture-retention.

Its buffering properties support skin barrier function in high-end personal care. Food and beverage producers also incorporate it into functional products such as fortified protein bars and recovery drinks.

Creatine is most commonly supplied as a fine white powder, with creatine monohydrate being the dominant commercial form. Food-grade and USP-grade specifications are standard for these applications.

Buyers typically source against established purity benchmarks for nutrition and pharmaceutical use. Micronized grades are also available for improved dispersibility in various finished formulations.

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Physical Properties

Melting Point 303 °C (decomp)
Boiling Point 242.43°C (rough estimate)
Density 1,33 g/cm 3
Color White to Off-White
Form Solid
Water Solubility Soluble in water.
Refractive Index 1.5700 (estimate)
Log P -1.258 (est)

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29252900
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

N-Methyl-N-guanylglycine|N-Carbamimidoyl-N-methylglycine|N-Amidinosarcosine|N-[(e)-AMINO(imino)methyl]-N-methylglycine|N-(aminoiminomethyl)-N-methylglycine|Kreatin|Creatin|alpha-Methylguanidino acetic acid

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