Guanidinoacetic acid

CAS Number
352-97-6
EC Number
206-529-5
Abbreviation
GAA

What is Guanidinoacetic acid?

Guanidinoacetic acid (CAS 352-97-6), also known as GAA or guanidoacetic acid, is the direct biosynthetic precursor to creatine.

Where is Guanidinoacetic acid used?

  • Animal nutrition and feed manufacturing: incorporated into livestock and poultry feed
  • Sports nutrition and dietary supplement manufacturing: formulated into capsules, powders, and blended products targeting creatine biosynthesis support
  • Pharmaceutical formulators use it as a reference compound and active intermediate in creatine-related drug and supplement development.
  • Personal care: humectant and buffering agent in skin-conditioning formulations

Commercial specifications

  • Packaging from kilogram quantities for R&D procurement to bulk metric ton supply

Other Names (Synonyms)

Guanidineacetic acid|Guanidoacetic acid|N-amidinoglycine|Guanyl glycine|Glycine, N-(aminoiminomethyl)-|Glycine, N-amidino-|N-(Aminoiminomethyl)glycine|Guanidine Acetate|GAA

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What are the physical properties of Guanidinoacetic acid?

Melting Point >300 °C
Boiling Point 218.88°C (rough estimate)
Density 1.4020 (rough estimate)
Appearance WHITE TO SLIGHTLY BEIGE FINE CRYSTALLINE POWDER
Color White to Off-White
Form Solid
Water Solubility 3.6g/L(15 ºC)
Refractive Index 1.4900 (estimate)

How is Guanidinoacetic acid classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to Guanidinoacetic acid?

HS Code 29252000
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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