Guanidinoacetic acid

Guanidinoacetic acid (CAS 352-97-6), also known as GAA or guanidoacetic acid, is the direct biosynthetic precursor to creatine and is produced commercially for use across nutritional, pharmaceutical, and personal care applications.

Its role as a creatine precursor positions it as a functional ingredient where creatine supplementation or metabolic support is the end objective. In animal nutrition and feed manufacturing, GAA is incorporated into livestock and poultry feed.

It is used as a creatine precursor to support muscle energy metabolism and improve feed conversion efficiency. Pharmaceutical formulators use it as a reference compound and active intermediate in creatine-related drug and supplement development.

In sports nutrition and dietary supplement manufacturing, GAA is formulated into capsules, powders, and blended products targeting creatine biosynthesis support. Personal care formulators have evaluated it as a humectant and buffering agent.

It is used in skin-conditioning formulations where amino acid-derived ingredients are preferred. Guanidinoacetic acid is supplied as a white crystalline powder and is available in feed-grade and technical-grade specifications.

Pharmaceutical-grade material is produced to USP or equivalent standards for supplement and drug applications. Packaging typically ranges from kilogram quantities for R&D procurement to bulk metric ton supply.