Glutaric acid

CAS Number
110-94-1
EC Number
203-817-2

What is Glutaric acid?

Glutaric acid (CAS 110-94-1), also known commercially as glutarate, is a five-carbon dicarboxylic acid used as a pH buffer, acidulant, and reactive intermediate.

Where is Glutaric acid used?

  • Pharmaceuticals: co-former in API salt development and cocrystal development for solubility and stability
  • Personal care: mild acidulant and buffering agent in skin care
  • Food and flavoring: mild acidic note and preservation in processed food systems
  • Industrial synthesis: precursor for polyesters, plasticizers, and specialty polymers in coatings and resins
  • Its bifunctional acid structure makes it a practical building block for synthesis.

Good to know: Controlled pH affects preservative efficacy and shelf life in cosmetic formulations. Food-grade and pharmaceutical-grade material is available, the latter typically conforming to USP or BP specifications.

Other Names (Synonyms)

Pentandioic acid|Glutarate|1,5-pentanedioic acid|1,5-Pentanedioate|1,3-Propanedicarboxylate|Pentanedioic acid|1,3-Propanedicarboxylic acid|n-Pyrotartaric acid

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What are the physical properties of Glutaric acid?

Melting Point 97.5-98 °C
Boiling Point 200 °C @ Press: 20 Torr
Density 1.429 g/cm³ @ Temp: 15 °C
Flash Point 200°C/20mm
Appearance white or off-white crystals
Color Orange
Form Crystalline Powder
Water Solubility 430 g/L (20 ºC)
Vapor Pressure 0.022 hPa (18.5 °C)
Refractive Index nD106 1.41878
pH 3.7(1 mM solution);3.17(10 mM solution);2.66(100 mM solution)
Log P -0.26 at 25℃

How is Glutaric acid classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant

Hazard Statements

H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H319 Causes serious eye irritation

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P316 Get emergency medical help immediately.

Which trade and regulatory codes apply to Glutaric acid?

HS Code 29171990
Storage Class 8A - Combustible corrosive hazardous materials
WGK (Germany) 1
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