SoleChem

Phthalic acid

CAS
88-99-3
EC
201-873-2
Mol. Weight
166.13 g/mol

Description

Phthalic acid (CAS 88-99-3), also known as orthophthalic acid, is an aromatic dicarboxylic acid used across pharmaceutical, cosmetic, and specialty chemical manufacturing. It functions primarily as a pH buffer, acidulant, and catalyst precursor in synthesis and formulation processes.

In pharmaceutical manufacturing, phthalic acid serves as a buffering agent in tablet coatings and controlled-release formulations where precise pH management affects drug dissolution profiles. Cosmetic formulators incorporate it into pH-adjustment systems for creams and serums.

These rinse-off products require stability across a defined acidity range which is critical to shelf life. As a catalyst precursor, it is used in the production of phthalate esters and specialty resins where the acid form is the preferred starting material.

In preservation systems, its acidic character contributes to microbial control in formulations where low-pH environments are part of the preservation strategy. This versatility makes it a staple in modern chemical synthesis and industrial applications.

Phthalic acid is supplied as a white crystalline powder. Pharmaceutical-grade material meeting USP and BP specifications is available for regulated applications, ensuring high purity and compliance with international standards.

Technical-grade product serves industrial synthesis and resin manufacturing where high-volume production is required. Packaging options typically range from kilogram-scale bags to bulk sacks depending on the specific application volume and logistics.

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Physical Properties

Melting Point 191 °C (decomp)
Boiling Point 214.32°C (rough estimate)
Density 1.593 g/cm³ @ Temp: 15 °C
Flash Point 168 °C
Appearance white crystals
Color White
Form Powder
Water Solubility 7 g/L (25 ºC)
Vapor Pressure 7.8 hPa (191 °C)
Refractive Index 1.5100 (estimate)
pH 2 (5g/l, H2O, 20℃)
Log P 0.73 at 20℃

Safety & Handling (Learn More)

Danger GHS08 GHS05 GHS07
Hazard Statements
H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29173980
Storage Class 11 - Combustible Solids
WGK (Germany) 1

Documentation

Other Names

orthophthalic acid|o-dicarboxybenzene|o-carboxybenzoic acid|o-benzenedicarboxylic acid|Naphthalinic acid|Alizarinic acid|M 2|Sunftal 20

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