Aminoguanidine hydrochloride

CAS Number
1937-19-5
EC Number
217-707-7

What is Aminoguanidine hydrochloride?

Aminoguanidine hydrochloride (CAS 1937-19-5), also known as Pimagedine hydrochloride, is a reactive guanidine derivative used primarily as a pharmaceutical intermediate and biochemical research reagent.

Where is Aminoguanidine hydrochloride used?

  • Pharmaceutical synthesis: intermediate for heterocyclic compounds, triazines, aminotriazoles and guanidine-based APIs
  • Biotechnology research: carbonyl-scavenging activity in advanced glycation end-product assays and compound screening
  • Specialty agrochemical and fine chemical synthesis: catalyst or reactive intermediate for guanidine scaffolds
  • Contract manufacturers and API producers use it as a starting material for multi-step routes to cardiovascular and metabolic disease candidates.

Commercial specifications

  • High-purity grades
  • Packaging from small laboratory quantities to multi-kilogram industrial lots

Other Names (Synonyms)

Pimagedine hydrochloride|Aminoguanidine hcl|2-aminoguanidine;hydrochloride|Aminoguanidinium chloride

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What are the physical properties of Aminoguanidine hydrochloride?

Melting Point 160-162 °C
Appearance white to off-white crystals
Color White to off-white
Form Crystals
Water Solubility 506.7g/L at 20℃
Vapor Pressure 0Pa at 25℃
Log P -3.55 at 20℃

How is Aminoguanidine hydrochloride classified and handled safely? Learn More

Danger
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H360 May damage fertility or the unborn child

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Aminoguanidine hydrochloride?

HS Code 29280000
Storage Class 13 - Non Combustible Solids
WGK (Germany) 3
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