Amines REACH

Glucamine

CAS Number
488-43-7
EC Number
207-677-3

What is Glucamine?

Glucamine (CAS 488-43-7) is an amino sugar alcohol used as a pH buffer, chelating agent, and humectant.

Where is Glucamine used?

  • Pharmaceuticals: salt complexes with acidic active ingredients, improving solubility and bioavailability in oral and injectable drug products
  • Cosmetics: pH buffering in moisturizing creams and serums
  • Skin care: humectant that supports water retention in the stratum corneum for leave-on products targeting dry or sensitive skin
  • Food and nutritional supplements: processing aid and buffering component in mineral delivery systems
  • It binds trace metal ions that would otherwise destabilize the formulation.

Good to know: It is the free amine base form commonly encountered in API salt formation and topical formulation chemistry.

Commercial specifications

  • Packaging from kilogram-scale laboratory quantities to multi-kilogram bulk

Other Names (Synonyms)

1-Amino-1-deoxy-D-glucitol|5QN16UUF80|RefChem:663086|GlyTouCan:G24280RP|G24280RP|D-Glucitol, 1-amino-1-deoxy-|Glucitol, 1-amino-1-deoxy-, D-

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What are the physical properties of Glucamine?

Melting Point 127 °C
Boiling Point 314.29°C (rough estimate)
Density 1.3243 (rough estimate)
Flash Point 230°C
Appearance Crystalline Solid
Color White to Pale Yellow
Form Solid
Refractive Index -7 ° (C=10, H2O)

How is Glucamine classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation

Precautionary Statements

P264 Wash … thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P321 Specific treatment (see … on this label).
P264+P265 Wash … thoroughly after handling.

Which trade and regulatory codes apply to Glucamine?

HS Code 29400090
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