L-alanyl-L-glutamine

L-alanyl-L-glutamine (CAS 39537-23-0), commonly referenced as Ala-Gln or L-Ala-L-Gln, is a dipeptide of alanine and glutamine valued for its superior aqueous stability compared to free glutamine. Across pharmaceutical, nutraceutical, and cosmetic markets, it functions as a bioavailable glutamine source, humectant, and stabilizing agent in formulations where glutamine alone would degrade.

In parenteral and enteral nutrition products, Ala-Gln is the preferred glutamine delivery form because it remains stable in solution during sterilization and extended storage. Sports nutrition and functional food formulators incorporate it into ready-to-drink beverages and protein supplements where free glutamine solubility and shelf-life are limiting factors.

Cosmetic chemists use it in skin-conditioning serums, moisturizing creams, and post-procedure topical products for its humectant and antioxidant-stabilizing properties. In cell culture media, it replaces unstable L-glutamine to maintain consistent nutrient availability across biopharmaceutical manufacturing processes.

L-alanyl-L-glutamine is supplied as a white crystalline powder. It is available in pharmaceutical-grade and food-grade specifications, with FEMA 4712 designation supporting its use. Bulk quantities are standard for industrial buyers, with smaller research-grade quantities available for formulation development to meet various industry requirements.