D-alanine
Description
D-Alanine (CAS 338-69-2), also known as D-Ala, is the D-enantiomer of the naturally occurring amino acid alanine. It functions as a chiral building block, buffering agent, and stabilizer across pharmaceutical and cosmetic applications.
Demand is driven primarily by its role in synthesizing peptide-based active ingredients and pharmaceutical intermediates where enantiomeric purity is critical. In pharmaceutical manufacturing, it is used as a chiral intermediate.
It is essential in the synthesis of peptide antibiotics, enzyme inhibitors, and other stereospecific active compounds. Cosmetic formulators incorporate it into skin care products for its moisturizing and pH-buffering properties.
It is particularly effective in serums and treatment creams targeting hydration. In food and nutrition, it functions as a flavor modifier and stabilizer in specialty formulations, including amino acid-enriched dietary supplements.
Research and peptide synthesis laboratories also source it as a building block for custom peptide sequences requiring non-natural amino acid incorporation. This versatility makes it a staple in modern chemical synthesis.
The product is supplied as a white crystalline powder. It is available in pharmaceutical-grade (USP/BP) and reagent-grade specifications to meet the purity requirements of different industrial end markets.
Packaging ranges from small quantities for laboratory and R&D use to bulk quantities for industrial peptide synthesis. We ensure high-quality standards for commercial formulation and large-scale manufacturing needs.
Physical Properties
| Melting Point | 292 °C |
| Boiling Point | 212.9±23.0 °C(Predicted) |
| Density | 1.4310 (estimate) |
| Appearance | White Crystalline Powder |
| Color | White to off-white |
| Odor | odorless |
| Form | Crystalline Powder or Crystals |
| Water Solubility | 155 g/L (20 ºC) |
| Refractive Index | -14 ° (C=2, 6mol/L HCl) |
| Log P | -0.574 (est) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29224900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
(2R)-2-aminopropanoic acid|D-2-Aminopropionic acid|D-Ala|D-alpha-Alanine|Alanine, D-|Alanine D-form|(R)-2-Aminopropionic acid|Ba 2776
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