Alpha lipoic acid
Description
Alpha lipoic acid (CAS 1077-28-7) is a sulfur-containing antioxidant compound used across pharmaceutical, nutraceutical, and cosmetic manufacturing. It functions primarily as an antioxidant and cellular cofactor.
The material is used in both finished dosage forms and active ingredient formulations. In nutraceuticals and dietary supplements, it is formulated into capsules, tablets, and functional foods targeting metabolic support.
Cosmetic formulators incorporate it into anti-aging creams and serums where its antioxidant activity supports oxidative stability. Its skin-conditioning performance makes it a versatile choice for high-end topical applications.
Pharmaceutical manufacturers use it as an active ingredient in intravenous and oral preparations. This is common in markets where it holds drug status for specific neuropathic indications and therapeutic uses.
In food-grade applications, it is evaluated as an antioxidant stabilizer in fortified products and functional beverage systems. It helps maintain the integrity of complex formulations during the manufacturing process.
The product is supplied as a fine crystalline yellow powder. Standard grades include pharmaceutical-grade material meeting USP and Ph. Eur. specifications for global compliance and safety.
Food-grade and cosmetic-grade options are also available for non-pharmaceutical applications. Bulk quantities are provided for industrial-scale formulation to meet the demands of large-scale production facilities.
R-alpha lipoic acid is also available as a distinct enantiomer-specific grade for premium supplement applications. This specialized version offers targeted benefits for manufacturers seeking high-potency ingredients.
Physical Properties
| Melting Point | 60-61 °C |
| Boiling Point | 160-165 °C |
| Density | 1.2888 (rough estimate) |
| Flash Point | 160-165°C |
| Appearance | Light-Yellow Solid |
| Color | Yellow |
| Form | Crystals or Crystalline Powder |
| Water Solubility | 0.9 g/L (20 ºC) |
| Refractive Index | 1.5200 (estimate) |
| Log P | 2.530 (est) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29349900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
liponic acid|acetate-replacing factor|6,8-thiotic acid|6,8-thioctic acid|6-thiotic acid|6-thioctic acid|5-[3-(1,2-dithiolanyl)]pentanoic acid|5-(dithiolan-3-yl)pentanoic acid|ALA
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