Vitamin B6 Pyridoxal 5'-Phosphate (P5P)

Vitamin B6 Pyridoxal 5'-Phosphate (P5P) (CAS 41468-25-1) is the biologically active coenzyme form of Vitamin B6, distinguished from precursor forms such as pyridoxine hydrochloride by its direct metabolic availability.

Where is Vitamin B6 Pyridoxal 5'-Phosphate (P5P) used?

• Nutraceutical and dietary supplements: active ingredient for capsules, tablets and softgels
• Food and functional food: fortified products, meal replacements and clinical nutrition
• Personal care and cosmetics: antioxidant and stabilising agent, with interest in scalp and hair care
• In pharmaceuticals it is sourced to USP or Ph. Eur. compendial specifications where applicable.

Good to know: It does not appear in the Annex II list under Regulation 1925/2006, so fortification claims should be assessed accordingly. Stability requires consideration during processing, particularly under elevated temperature or light exposure.

Commercial specifications

• Listed in Annex II of Directive 2002/46/EC as a permitted vitamin source under the designation pyridoxal 5'-phosphate
• Authorised EU health claims under Regulation (EC) No 432/2012 for Vitamin B6 include contributions to normal protein and glycogen metabolism, red blood cell formation, normal functioning of the immune system, homocysteine metabolism, and regulation of hormonal activity
• Documentation: certificate of analysis (COA), heavy metals testing, microbial limits, assay results, safety data sheet (SDS), regulatory support files
• Fine crystalline powder; 1 kg and 5 kg units, 25 kg fibre drums