Disodium NADH

Disodium NADH (CAS 606-68-8), commonly abbreviated as NADH, is the stabilized disodium salt form of the reduced coenzyme nicotinamide adenine dinucleotide. It functions as a bioactive coenzyme and antioxidant active across pharmaceutical, nutraceutical, and cosmetic applications. In pharmaceutical and nutraceutical manufacturing, NADH is formulated into oral supplements and clinical preparations targeting cognitive function, fatigue management, and neurological support. These applications focus on cellular energy metabolism support as the target outcome.

Cosmetic and personal care formulators incorporate it into anti-aging serums and moisturizing treatments. Its antioxidant activity helps protect against oxidative stress at the cellular level, making it a valuable ingredient for high-end skincare formulations. Biotechnology and life sciences operations use NADH as a cofactor in enzymatic assays and biosensor development. It is also essential in in vitro diagnostic reagent production and serves as a pharmaceutical intermediate for complex coenzyme-based active ingredients.

Disodium NADH is supplied as a lyophilized powder or fine crystalline solid, typically requiring cold-chain handling to maintain stability. Standard grades include research-grade and pharmaceutical-grade material to meet industry requirements. Purity specifications are commonly at 95% or higher by HPLC to ensure efficacy in sensitive applications. Packaging ranges from small quantities for laboratory and R&D procurement to bulk quantities for commercial formulation and large-scale manufacturing.