Etidronate disodium

CAS Number
7414-83-7
EC Number
230-458-3
Abbreviation
HEDP disodium

What is Etidronate disodium?

Etidronate disodium (CAS 7414-83-7), also known as HEDP disodium, is the disodium salt form of hydroxyethylidene diphosphonic acid used commercially as a chelating and sequestering agent.

Where is Etidronate disodium used?

  • Water treatment: controls calcium carbonate and metal oxide scale in cooling towers, boilers, and process water systems
  • Personal care: incorporated into shampoos and creams; sequesters trace metals in rinse-off products to prevent destabilisation of peroxide-based systems or rancidity
  • Textile and leather processing: deactivates hardness ions, improving process consistency and colour yield in dye baths and bleaching liquors
  • Pharmaceutical manufacturing: stabilising excipient in liquid formulations where oxidation must be controlled
  • It binds metal ions, particularly calcium and heavy metals, to prevent scale formation, oxidative degradation, and microbial activity.

Good to know: Material is available to meet USP and BP standards, with food-contact and cosmetic-grade material available to meet purity requirements for various regulated applications.

Commercial specifications

  • Solution concentrations typically around 30–40%

Other Names (Synonyms)

sodium etidronate|sodium ethydronate|sodium ethidronate|disodium etidronate|disodium ethydronate|disodium ethanol-1,1-diphosphonate|disodium ethane-1-hydroxy-1,1-diphosphonate|disodium dihydrogen (1-hydroxyethylidene)diphosphonate|HEDP disodium

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What are the physical properties of Etidronate disodium?

Melting Point >300 °C
Appearance White Crystalline Solid
Color white
Form solid
Water Solubility Soluble in water (26 mg/ml).

How is Etidronate disodium classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H319 Causes serious eye irritation
H413 May cause long lasting harmful effects to aquatic life

Precautionary Statements

P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to Etidronate disodium?

HS Code 29319090
WGK (Germany) 1
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