Tetrasodium EDTA

CAS Number
64-02-8
EC Number
200-573-9

What is Tetrasodium EDTA?

Tetrasodium EDTA (CAS 64-02-8), also known as Edetate Tetrasodium, is a fully neutralized sodium salt of ethylenediaminetetraacetic acid; a chelating and sequestering agent.

Where is Tetrasodium EDTA used?

  • Personal care and cosmetics: stabilizes formulations by deactivating trace metals
  • Industrial and household cleaners: sequester hardness ions, improving surfactant efficiency and preventing scale buildup on surfaces and equipment
  • Water treatment: controls metal ion concentrations and inhibits scale formation in process systems
  • Pharmaceutical manufacturing: chelating preservative aid, extending product stability
  • By binding calcium, magnesium, and heavy metal ions, it prevents mineral interference in formulations, process water, and finished products.

Good to know: These metals would otherwise degrade active ingredients or cause discoloration. This is particularly important in topical and injectable formulations where metal contamination must be tightly controlled.

Commercial specifications

  • Aqueous solutions typically at 40% concentration
  • Buyers should confirm grade and moisture content when sourcing.

Other Names (Synonyms)

Edetate Sodium|tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate

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What are the physical properties of Tetrasodium EDTA?

Melting Point >300 °C
Density Apparent density: 6.9 lb/gallon
Appearance Tetrasodium EDTA is a white crystalline solid.
Color White
Form Crystalline Powder
Log P -0.434 (est)

How is Tetrasodium EDTA classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Which trade and regulatory codes apply to Tetrasodium EDTA?

HS Code 29224985
WGK (Germany) 2
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