Disodium EDTA

CAS Number
139-33-3
EC Number
205-358-3
Chemical Formula
C10H16N2O8.2Na
Molecular Weight
336.21 g/mol
Abbreviation
Na2-EDTA

Description

Disodium EDTA (CAS 139-33-3), also known as Na2H2EDTA and listed as E386 in food applications, is a chelating agent that binds and neutralizes metal ions in formulations and processes. By sequestering calcium, magnesium, iron, and other trace metals, it prevents discoloration, rancidity, and scale formation across a broad range of industries and finished products.

In personal care and cosmetic formulations, it stabilizes emulsions and preservative systems by removing metal ions that would otherwise accelerate oxidative degradation during the shelf life. Food manufacturers use it under the E386 designation to protect canned vegetables, dressings, and seafood products from metal-catalyzed color and flavor loss during storage and processing.

Water treatment and industrial cleaning operations rely on it to sequester hardness ions, improving detergent efficiency and preventing mineral deposits in various types of process equipment. In pharmaceutical manufacturing, it functions as a stabilizer in liquid dosage forms and ophthalmic preparations where trace metal contamination must be tightly controlled for safety.

Disodium EDTA is supplied as a white crystalline powder or granules. Standard grades include food-grade, USP, BP, and Ph. Eur. specifications for pharmaceutical and regulated food applications. Technical grade is also available for industrial use. Bulk supply is available in bags and fiber drums, with packaging options suited to both formulation-scale and large industrial procurement.

Other Names (Synonyms)

Na2H2EDTA|Na2-EDTA|N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], disodium salt|ethylenediaminetetraacetic acid disodium salt|ethylenebis(iminodiacetic acid) disoidum salt|EDTA disodium salt (anh.)|EDTA disodium (anhydrous)|EDTA disodium (anh.)|E386

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 252 °C (decomp)
Boiling Point >100 °C
Density 1.01 g/mL at 25 °C
Appearance white crystalline solid
Color ≤5 (0.5 M)(APHA)
Odor Odorless
Form solution
Water Solubility Miscible with water.
Vapor Pressure 0Pa at 25℃
Refractive Index n20/D 1.363
pH 8.0±0.2
Log P -4.3 at 25℃

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
H373 May causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Trade & Regulatory

HS Code 29224900
Storage Class 12 - Non Combustible Liquids
WGK (Germany) 2
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