Chelating Agents
REACH
Disodium EDTA
CAS Number
139-33-3
EC Number
205-358-3
Abbreviation
Na2-EDTA
What is Disodium EDTA?
Disodium EDTA (CAS 139-33-3), also known as Na2H2EDTA and listed as E386 in food applications, is a chelating agent that binds and neutralizes metal ions in formulations and processes.
Where is Disodium EDTA used?
- Personal care and cosmetics: stabilizes emulsions and preservative systems by removing metal ions that accelerate oxidative degradation
- Food: protects canned vegetables, dressings and seafood from metal-catalyzed color and flavor loss under E386
- Water treatment and industrial cleaning: sequesters hardness ions, improving detergent efficiency and preventing mineral deposits in process equipment
- In pharmaceutical manufacturing it functions as a stabilizer in liquid dosage forms and ophthalmic preparations.
Commercial specifications
- Bags and fiber drums for formulation-scale and large industrial procurement
Other Names (Synonyms)
Na2H2EDTA|Na2-EDTA|N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], disodium salt|ethylenediaminetetraacetic acid disodium salt|ethylenebis(iminodiacetic acid) disoidum salt|EDTA disodium salt (anh.)|EDTA disodium (anhydrous)|EDTA disodium (anh.)|E386
What are the physical properties of Disodium EDTA?
Melting Point 252 °C (decomp)
Boiling Point >100 °C
Density 1.01 g/mL at 25 °C
Appearance white crystalline solid
Color ≤5 (0.5 M)(APHA)
Odor Odorless
Form solution
Water Solubility Miscible with water.
Vapor Pressure 0Pa at 25℃
Refractive Index n20/D 1.363
pH 8.0±0.2
Log P -4.3 at 25℃
How is Disodium EDTA classified and handled safely? Learn More
Warning
GHS07· Irritant GHS08· Health Hazard
Hazard Statements
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
H373 May causes damage to organs through prolonged or repeated exposure
Precautionary Statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Which trade and regulatory codes apply to Disodium EDTA?
HS Code 29224900
Storage Class 12 - Non Combustible Liquids
WGK (Germany) 2