Tetrasodium edetate dihydrate

CAS Number
10378-23-1
EC Number
600-485-4
Abbreviation
EDTA-4Na

What is Tetrasodium edetate dihydrate?

Tetrasodium edetate dihydrate (CAS 10378-23-1), commercially known as EDTA-4Na, is a fully neutralized sodium salt of EDTA in hydrated form.

Where is Tetrasodium edetate dihydrate used?

  • Personal care and cosmetics: stabilizes formulations by deactivating trace metals that would otherwise degrade preservative systems
  • Water treatment: sequesters hardness ions and controls scale formation in industrial circuits
  • Textile and leather processing: prevents metal-catalyzed oxidation during bleaching and dyeing
  • Food-compatible applications: sequestrant that maintains product stability and extends shelf life where metal contamination is a processing risk
  • It functions as a chelating and sequestering agent, binding metal ions such as calcium and magnesium.

Good to know: By binding iron and copper, it prevents these metal ions from interfering with formulations, processes, or finished products.

Commercial specifications

  • Packaging ranges from small bags to bulk quantities
  • Concentration typically expressed on a dihydrate basis

Other Names (Synonyms)

EDTA tetrasodium salt dihydrate|Ethylenediaminetetraacetic acid tetrasodium salt dihydrate|Tetrasodium ethylenediaminetetraacetate dihydrate|3JGX4KKZ4A|Acetic acid, (ethylenedinitrilo)tetra-, tetrasodium salt, dihydrate|EDETIC ACID TETRASODIUM SALT DIHYDRATE|GLYCINE, N,N'-1,2-ETHANEDIYLBIS(N-(CARBOXYMETHYL)-, SODIUM SALT, HYDRATE (1:4:2)|GLYCINE, N,N'-1,2-ETHANEDIYLBIS(N-(CARBOXYMETHYL)-, TETRASODIUM SALT, DIHYDRATE|EDTA-4Na

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What are the physical properties of Tetrasodium edetate dihydrate?

Melting Point >300°C
Flash Point 350°C
Appearance white crystals or powder
Color Yellow-Orange
Form Liquid
Water Solubility almost transparency
pH 10.5-11.5 (50g/l, H2O, 20℃)

How is Tetrasodium edetate dihydrate classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Tetrasodium edetate dihydrate?

HS Code 29224999
WGK (Germany) 3
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