Disodium EDTA dihydrate

CAS Number
6381-92-6
EC Number
613-386-6
Chemical Formula
C10H16N2O8.2H2O.2Na
Molecular Weight
372.24 g/mol
E Number
E383
FEMA Number
FEMA 4520
Abbreviation
EDTA

Description

Disodium EDTA dihydrate (CAS 6381-92-6) is the dihydrate form of the disodium salt of ethylenediaminetetraacetic acid, commonly sourced under the abbreviation EDTA disodium. It functions as a chelating and sequestering agent. By binding metal ions, it prevents oxidation, discoloration, and microbial activity across a broad range of industrial and consumer product applications. In personal care and cosmetics, it stabilizes formulations by deactivating trace metals.

This prevents the degradation of preservatives or the development of rancidity in creams, shampoos, and lotions. Food and beverage manufacturers use it to prevent metal-catalyzed oxidation in canned goods and dressings. It is particularly effective in seafood products where color and shelf life are critical quality parameters. Water treatment operations deploy it to sequester calcium and magnesium ions, controlling scale formation in industrial systems.

In pharmaceutical manufacturing, it enhances preservative efficacy in ophthalmic and injectable formulations. It achieves this by chelating metal cofactors that support microbial growth in sensitive medical products. Disodium EDTA dihydrate is supplied as a white crystalline powder. Standard grades include food-grade (FCC), USP, BP, and Ph. Eur., supporting procurement across various highly regulated industries.

Technical grade is also available for industrial applications such as textile processing and leather treatment. It is widely used in water treatment where specific pharmacopeial certification is not strictly required.

Other Names (Synonyms)

Na2H2EDTA.2H2O|ethylenediaminetetraacetic acid disodium salt dihydrate|EDTA disodium dihydrate|edetate disodium|disodium edetate dihydrate|disodium (ethylenedinitrilo)tetraacetate dihydrate|EDTA disodium salt|Edta disodium|EDTA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 250 °C (dec.)(lit.)
Boiling Point >100 °C
Density 1.01 g/mL at 25 °C
Flash Point >100°C
Appearance White crystalline powder
Color ≤5 (0.5 M)(APHA)
Odor Odorless
Form crystalline
Water Solubility soluble
Refractive Index n 20/D 1.363
pH 4.0-5.5 (25℃, 0.1M in H2O)

Safety & Handling (Learn More)

Warning
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
H373 May causes damage to organs through prolonged or repeated exposure
H412 Harmful to aquatic life with long lasting effects

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29224995
Storage Class 11 - Combustible Solids
WGK (Germany) 2

Documentation

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