Vitamin B3 Nicotinamide

CAS Number
98-92-0
EC Number
202-713-4
Chemical Formula
C6H6N2O
Molecular Weight
122.12 g/mol
Abbreviation
NAM

Description

Nicotinamide (CAS 98-92-0), also known as niacinamide and designated E375 in food applications, is the amide form of vitamin B3 used across pharmaceutical, nutritional, and cosmetic manufacturing. It functions as an active nutrient, skin-conditioning agent, and formulation stabilizer depending on the end market. In pharmaceutical manufacturing, it is used as an active ingredient in vitamin B3 supplements.

It is found in multivitamin tablets and therapeutic preparations targeting pellagra and metabolic disorders. Food and beverage producers use it as an approved nutrient fortifier in cereals, infant formula, and functional drinks. In these applications, it restores or enhances B-vitamin content. Cosmetic formulators incorporate niacinamide into serums, moisturizers, and anti-aging creams for its ability to support skin barrier function.

It helps reduce hyperpigmentation and also appears in feed premixes and veterinary nutritional products as a cost-effective B-vitamin source. The material is supplied as a white crystalline powder. It is available in both food-grade and pharmaceutical-grade specifications. Recognized quality standards include USP, BP, Ph. Eur., and FCC, ensuring high purity for various industrial uses.

Pharmaceutical grades are subject to stricter purity and heavy metal limits. Bulk supply is standard in 25 kg bags, with smaller packaging available for specialty or cosmetic-grade orders.

Other Names (Synonyms)

Nicotinamide|Vitamin B3 Niacinamide|pyridine-3-carboxamide|Niacinamide|NAM|E375

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 130 °C
Boiling Point 157 °C @ Press: 5 x 10-4 Torr
Density 1.400 g/cm³ @ Temp: 25 °C
Flash Point 182 °C
Appearance White crystalline powder
Color white
Odor Odorless
Form powder
Water Solubility 1000 g/L (20 ºC)
Vapor Pressure 0Pa at 25℃
Refractive Index 1.4660 (estimate)
pH 6.0-7.5 (50g/l, H2O, 20℃)
Log P -0.38 at 21℃

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Trade & Regulatory

HS Code 29362990
UN Number 1230
Packing Group II
WGK (Germany) 1
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