Menadione nicotinamide bisulfite

Menadione nicotinamide bisulfite (CAS 73581-79-0) is a water-soluble complex of menadione and nicotinamide, formulated to deliver stable vitamin K3 activity in aqueous systems. Its bisulfite complexation resolves the handling and solubility limitations of menadione.

This chemical structure makes it highly practical for liquid and feed premix manufacturing where the parent compound alone would be unsuitable. In animal nutrition, it serves as the primary source of supplemental vitamin K3 in poultry and swine.

It is also essential for aquaculture feed premixes, where water solubility is critical for uniform dosing. Pharmaceutical manufacturers incorporate it into injectable and oral liquid formulations requiring a stabilized, water-compatible vitamin K source.

In food and nutrition applications, it functions as a vitamin K3 fortification agent in products where dry menadione would present processing challenges. Its antioxidant properties support stability in multi-vitamin concentrate blends.

The compound is also valued for its preservative properties across feed and nutraceutical production. Menadione nicotinamide bisulfite is supplied as a white to off-white crystalline powder for various industrial applications.

Standard commercial grades include feed-grade and pharmaceutical-grade specifications. Feed-grade material is commonly standardized to 50% menadione activity to ensure consistent nutritional delivery in large scale manufacturing.

Pharmaceutical-grade material is available to USP and BP specifications for use in regulated drug product manufacturing. These high purity standards ensure the material meets rigorous safety and efficacy requirements for global distribution.