Menadione dimethylpyrimidinol bisulfite

Menadione dimethylpyrimidinol bisulfite (CAS 14451-99-1), commercially known as Hetrazeen, is a stabilized, water-soluble form of menadione used as a source of vitamin K activity in animal nutrition and pharmaceutical applications. Its bisulfite complex form improves handling and formulation compatibility compared to free menadione, making it a practical choice for manufacturers requiring a stable K-vitamin source.

In animal feed manufacturing, it is incorporated into premixes and complete feeds to support vitamin K supplementation in poultry, swine, and aquaculture diets for various livestock. Pharmaceutical formulators use it as an active ingredient in veterinary preparations where a water-dispersible vitamin K source is required for effective treatment and health maintenance.

In nutritional supplement production, it enables precise dosing in liquid and powder formats where free menadione would present significant stability challenges during the manufacturing process. Its antioxidant and preservation profile also supports its evaluation in formulations requiring oxidative stability alongside vitamin activity to ensure long-term product efficacy and shelf life.

Menadione dimethylpyrimidinol bisulfite is supplied as a crystalline powder and is available in feed-grade and technical-grade specifications for industrial and commercial use. Product quality is typically assessed against established feed additive standards. Bulk supply is standard for premix operations, with smaller quantities available for research applications.