SoleChem

Phylloquinone

CAS
84-80-0
EC
201-564-2
Mol. Weight
450.7 g/mol

Description

Phylloquinone (CAS 84-80-0), commercially recognized as Vitamin K1, is the naturally occurring form of vitamin K derived primarily from plant sources. It functions as a bioactive nutrient in food fortification and pharmaceutical formulations.

This compound is also utilized in cosmetic preparations where coagulation-related and skin-conditioning activity is required. In pharmaceutical manufacturing, it is formulated into injectable solutions, oral capsules, and tablets.

These products target vitamin K deficiency and anticoagulant reversal protocols. Food and infant formula producers use it to fortify products to meet regulatory nutrient reference values across major global markets.

In cosmetic formulations, it is incorporated into eye creams, serums, and post-procedure skincare products. These applications target the appearance of dark circles and bruising through topical delivery systems.

Clinical nutrition manufacturers also include it in parenteral and enteral nutrition products requiring complete micronutrient profiles. It is supplied as a viscous oil in its pure form for various industrial uses.

Emulsified and water-dispersible formats are available for aqueous formulation systems. Standard grades include USP, BP, and Ph. Eur., supporting pharmaceutical and clinical nutrition applications.

Food-grade material meeting FCC specifications is available for dietary supplement and fortified food production. This ensures compliance with international safety and quality standards for human consumption.

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Physical Properties

Melting Point -20 °C
Boiling Point 140-145 °C @ Press: 1 x 10-3 Torr
Density 0.964 g/cm³ @ Temp: 25 °C
Flash Point >230 °F
Appearance Phylloquinone is an odorless yellow viscous oil or crystals.
Color Yellow to Dark Yellow
Odor odorless
Form viscous liquid
Water Solubility Miscible with dehydrated alcohol, acetone, petroleum ether, hexane, dioxane, chloroform, ether, benzene and vegetable oils. Immiscible with water.
Refractive Index n 20/D 1.527(lit.)
Log P 10.305 (est)

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H317 May cause an allergic skin reaction
H413 May cause long lasting harmful effects to aquatic life
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P321 Specific treatment (see … on this label).
P501 Dispose of contents/container in accordance with local regulations.
P302+P352 IF ON SKIN: Wash with plenty of water.
P333+P317 Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.

Trade & Regulatory

HS Code 29369000
UN Number 1170
Packing Group II
Storage Class 10 - Combustible liquids
WGK (Germany) 2

Documentation

Other Names

Vitamin K1|Vitamin k|trans-Phylloquinone|Synthex P|Phythyl-menadion|Monodion|Mono-Kay|Mephyton

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