Cholecalciferol
Description
Cholecalciferol (CAS 67-97-0), also known as Vitamin D3, is the animal-derived form of vitamin D used across food fortification, dietary supplements, animal feed, and pharmaceutical manufacturing.
It supports calcium and phosphorus metabolism regulation, making it a critical active ingredient for bone health and nutritional product development in various industrial applications.
In food and beverage manufacturing, cholecalciferol is used to fortify dairy products, plant-based milks, cereals, and infant formula to meet established nutritional labeling standards.
Premix and supplement manufacturers incorporate it into softgels, tablets, and powdered blends where precise dosing and stability in oil-based carriers are required for the final product.
Animal feed producers use it to support skeletal development and egg production performance in poultry, swine, and aquaculture operations to ensure optimal livestock health and yield.
Pharmaceutical-grade cholecalciferol is also used as the active in prescription and OTC vitamin D3 formulations, including drops and oral solutions targeting deficiency treatment.
Cholecalciferol is supplied as an oily liquid concentrate, dry powder, or microencapsulated beadlet form to suit different manufacturing processes and stability requirements.
Recognized grades include USP, BP, Ph. Eur., and food-grade specifications to meet regulatory requirements across pharmaceutical, nutraceutical, and feed markets.
Physical Properties
| Melting Point | 84-85 °C |
| Boiling Point | 451.27°C (rough estimate) |
| Density | 0.939 g/cm³ |
| Flash Point | 14 °C |
| Appearance | Crystalline |
| Color | White |
| Odor | odorless |
| Form | powder |
| Water Solubility | <0.1 g/L (20 ºC) |
| Vapor Pressure | 2.0 x l0 -6 Pa (20 °C, est.) |
| Refractive Index | 1.5100 (estimate) |
| Log P | 9.085 (est) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29362990 |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| WGK (Germany) | 2 |
Documentation
Other Names
oleovitamin D3|delta-D|activated 7-dehydrocholesterol|9,10-secocholesta-5,7,10(19)-trien-3beta-ol|9,10-secocholesta-5,7,10(19)-trien-3-ol|9,10-secocholesta-5,7,10-trien-3-ol|3-beta,Z,7E-9,10-secocholestr-5,7,10(19)-trien-3-ol|(5Z,7e)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
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