Vitamin D3 Cholecalciferol

CAS Number
67-97-0
EC Number
200-673-2
Chemical Formula
C27H44O
Molecular Weight
384.6 g/mol

Description

Cholecalciferol (CAS 67-97-0), also known as Vitamin D3, is the animal-derived form of vitamin D used across food fortification, dietary supplements, animal feed, and pharmaceutical manufacturing. It supports calcium and phosphorus metabolism regulation, making it a critical active ingredient for bone health and nutritional product development in various industrial applications.

In food and beverage manufacturing, cholecalciferol is used to fortify dairy products, plant-based milks, cereals, and infant formula to meet established nutritional labeling standards. Premix and supplement manufacturers incorporate it into softgels, tablets, and powdered blends where precise dosing and stability in oil-based carriers are required for the final product.

Animal feed producers use it to support skeletal development and egg production performance in poultry, swine, and aquaculture operations to ensure optimal livestock health and yield. Pharmaceutical-grade cholecalciferol is also used as the active in prescription and OTC vitamin D3 formulations, including drops and oral solutions targeting deficiency treatment.

Cholecalciferol is supplied as an oily liquid concentrate, dry powder, or microencapsulated beadlet form to suit different manufacturing processes and stability requirements. Recognized grades include USP, BP, Ph. Eur., and food-grade specifications to meet regulatory requirements across pharmaceutical, nutraceutical, and feed markets.

Other Names (Synonyms)

Cholecalciferol|oleovitamin D3|delta-D|activated 7-dehydrocholesterol|9,10-secocholesta-5,7,10(19)-trien-3beta-ol|9,10-secocholesta-5,7,10(19)-trien-3-ol|9,10-secocholesta-5,7,10-trien-3-ol|3-beta,Z,7E-9,10-secocholestr-5,7,10(19)-trien-3-ol|(5Z,7e)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 84-85 °C
Boiling Point 451.27°C (rough estimate)
Density 0.939 g/cm³
Flash Point 14 °C
Appearance Crystalline
Color White
Odor odorless
Form powder
Water Solubility <0.1 g/L (20 ºC)
Vapor Pressure 2.0 x l0 -6 Pa (20 °C, est.)
Refractive Index 1.5100 (estimate)
Log P 9.085 (est)

Documentation

Safety & Handling Learn More

Danger
GHS06· Toxic GHS08· Health Hazard

Hazard Statements

H300 Fatal if swallowed
H301 Toxic if swallowed
H310 Fatal in contact with skin
H311 Toxic in contact with skin

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash … thoroughly after handling.

Trade & Regulatory

HS Code 29362990
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 2
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