Cyanocobalamin

CAS Number
68-19-9
EC Number
200-680-0
Chemical Formula
C63H88CoN14O14P
Molecular Weight
1355.4 g/mol

Description

Cyanocobalamin (CAS 68-19-9), commonly known as Vitamin B12, is the synthetic, stable form of cobalamin used across food, pharmaceutical, and cosmetic manufacturing. It functions as a bioactive nutrient supplement. This ingredient enables producers to fortify finished products with a measurable, shelf-stable B12 source. In pharmaceutical manufacturing, it is the active ingredient in injectable formulations, oral tablets, and sublingual preparations.

Food and beverage producers use it to fortify plant-based milks, breakfast cereals, and nutritional supplements. These are categories where B12 is often absent from natural ingredients, making fortification essential for consumers. In clinical nutrition, it is incorporated into enteral and parenteral nutrition products. Precise dosing and stability under various processing conditions are critical factors for these specialized medical applications.

Cosmetic formulators add it to serums and hair care products positioned around scalp health and skin radiance claims. It is supplied as a fine crystalline powder, typically in diluted trituration blends at concentrations of 0.1% or 1%. These blends use carriers such as mannitol or starch, allowing accurate dosing at low inclusion rates. Pure form is available for specialized applications requiring high potency and minimal additives.

Recognized grades include USP, BP, and Ph. Eur., ensuring high purity for pharmaceutical use. Food-grade material meets FCC specifications for use in fortified consumer products.

Other Names (Synonyms)

Vitamin B12 Cyanocobalamin|Cobalamin|cobalt(3+);[(2R,3S,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R)-1-[3-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-id-3-yl]propanoylamino]propan-2-yl] phosphate;cyanide|Vitamin B12

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point >300 °C
Boiling Point >300 °C
Flash Point 9°C
Appearance Crystalline
Color Red to dark red
Odor dark red cryst. or powd., odorless and tasteless
Form Crystalline Powder or Crystals
Water Solubility Soluble
pH 6.0 (20°C, 1g/L in H2O)
Log P 3.570 (est)

Trade & Regulatory

HS Code 29362600
Storage Class 11 - Combustible Solids
WGK (Germany) 1

Documentation

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