Vitamin B12 Cyanocobalamin

CAS Number
68-19-9
EC Number
200-680-0

What is Vitamin B12 Cyanocobalamin?

Cyanocobalamin (CAS 68-19-9), commonly known as Vitamin B12, is the synthetic, stable form of cobalamin used in food, pharmaceutical, and cosmetic manufacturing.

Where is Vitamin B12 Cyanocobalamin used?

  • Pharmaceutical manufacturing: active ingredient in injectable formulations, oral tablets, and sublingual preparations
  • Food and beverage: fortification of plant-based milks, breakfast cereals, and nutritional supplements
  • Clinical nutrition: incorporated into enteral and parenteral nutrition products
  • Cosmetics: added to serums and hair care products for scalp health and skin radiance claims
  • It functions as a bioactive nutrient supplement.

Good to know: Precise dosing and stability under various processing conditions are critical for specialized medical applications.

Commercial specifications

  • Fine crystalline powder, typically in diluted trituration blends at concentrations of 0.1% or 1%
  • Blends use carriers such as mannitol or starch, allowing accurate dosing at low inclusion rates
  • Pure form available for specialized applications requiring high potency and minimal additives
  • Grades include USP, BP, Ph. Eur., and FCC specifications

Other Names (Synonyms)

Cyanocobalamin|Cobalamin|cobalt(3+);[(2R,3S,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R)-1-[3-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-id-3-yl]propanoylamino]propan-2-yl] phosphate;cyanide|Vitamin B12

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What are the physical properties of Vitamin B12 Cyanocobalamin?

Melting Point >300 °C
Boiling Point >300 °C
Flash Point 9°C
Appearance Crystalline
Color Red to dark red
Odor dark red cryst. or powd., odorless and tasteless
Form Crystalline Powder or Crystals
Water Solubility Soluble
pH 6.0 (20°C, 1g/L in H2O)
Log P 3.570 (est)

Which trade and regulatory codes apply to Vitamin B12 Cyanocobalamin?

HS Code 29362600
Storage Class 11 - Combustible Solids
WGK (Germany) 1
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