Methylcobalamin

Methylcobalamin (CAS 13422-55-4), also known as MeB12, is the bioactive, coenzyme form of vitamin B12 used as an active pharmaceutical ingredient in neurological and nutritional supplement formulations.

Unlike synthetic cyanocobalamin, it is the form directly utilized in human metabolism, making it the preferred choice for finished-dose manufacturers targeting premium positioning in the market.

In pharmaceutical manufacturing, this ingredient is formulated into oral tablets, sublingual preparations, and injectable solutions targeting peripheral neuropathy, cognitive support, and B12 deficiency indications.

Nutraceutical producers incorporate it into high-potency B-complex supplements and combination neurological formulas where bioavailability claims are a commercial differentiator for the final consumer product.

In cosmetic and personal care formulations, it is used in topical serums and scalp treatments where B12 activity is positioned around skin renewal and hair health for specialized beauty applications.

Contract manufacturers also source it as an intermediate for combination API blends in prescription neuropathy products. It is supplied as a dark red crystalline powder in light-protected packaging.

Standard grades include USP, BP, and Ph.Eur., with food-grade and cosmetic-grade material also available depending on the specific application and regulatory requirements of the region.

Bulk quantities are offered in kilogram and multi-kilogram lots, with high-purity specifications commonly at 98% or above to ensure the highest quality for industrial chemical processing.