Vitamins
REACH
S-Adenosyl-L-Methionine (SAMe)
CAS Number
29908-03-0
EC Number
249-946-8
Abbreviation
SAMe
What is S-Adenosyl-L-Methionine (SAMe)?
S-adenosylmethionine (CAS 29908-03-0), commonly known as SAMe or AdoMet, is a naturally occurring methyl donor central to enzymatic transmethylation reactions.
Where is S-Adenosyl-L-Methionine (SAMe) used?
- Pharmaceutical and nutraceutical manufacturing: oral supplements and prescription products for liver function support and mood-related indications
- Biochemistry and drug discovery: reference standard and reaction substrate in methyltransferase assays, epigenetics research, and enzyme kinetics studies
- Cosmetic formulations: anti-aging and skin-conditioning products where methyl donor activity supports cellular repair pathways
- Contract manufacturers producing enteric-coated tablets rely on stabilized SAMe salts.
Commercial specifications
- Cosubstrate in over 100 enzymatic reactions
- Pharmaceutical-grade material to USP and BP specifications; research-grade at defined purity levels
- Packaging from small R&D quantities to bulk commercial manufacturing quantities
Other Names (Synonyms)
S-adenosylmethionine|AdoMet|SAM|SAMe|S-adenosyl-L-methionine|S-(5'-deoxyadenosin-5'-yl)-L-methionine|(3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine, inner salt|Active methionine|RefChem:53996
What are the physical properties of S-Adenosyl-L-Methionine (SAMe)?
Color White to Yellow
Form Solid
How is S-Adenosyl-L-Methionine (SAMe) classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H302 Harmful if swallowed
H312 Harmful in contact with skin
H319 Causes serious eye irritation
H332 Harmful if inhaled
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
Which trade and regulatory codes apply to S-Adenosyl-L-Methionine (SAMe)?
HS Code 29349990