S-adenosyl-L-methionine disulfate tosylate

S-adenosyl-L-methionine disulfate tosylate (CAS 97540-22-2), commercially known as SAMe or ademetionine disulfate tosylate, is the stabilized salt form of SAM-e used across pharmaceutical, nutraceutical, and biotech manufacturing. The disulfate tosylate salt form provides the chemical stability required for commercial-scale production and formulation of finished dosage products. In pharmaceutical manufacturing, SAMe serves as the active ingredient in prescription and OTC products.

These products target liver function support and mood health, with finished forms including enteric-coated tablets and injectable preparations. Nutraceutical formulators use it as the basis for dietary supplement products marketed for joint comfort. It is also used for cognitive support, where dosage stability and bioavailability are primary sourcing criteria. Biotech and life sciences applications include use as a methyl donor substrate in enzymatic assays and cell culture research.

The material is further utilized in methylation pathway studies. Food-grade and functional nutrition applications leverage its antioxidant properties to support product stability in specialized clinical nutrition formulations. S-adenosyl-L-methionine disulfate tosylate is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications, including USP and EP-compliant grades.

Purity levels are typically at 95% or higher for industrial use. Packaging ranges from small research quantities to bulk industrial volumes, with cold-chain handling standard for maintaining potency during transport.