S-adenosyl-L-methionine chloride

S-adenosyl-L-methionine chloride (CAS 24346-00-7), also known as SAM chloride, is a stabilized salt form of the endogenous methyl donor S-adenosylmethionine used across pharmaceutical, nutraceutical, and biotechnology applications. It functions primarily as a methyl group donor in enzymatic synthesis and as an active ingredient in formulations targeting liver health and mood support categories. In pharmaceutical manufacturing, it serves as a key intermediate.

SAM chloride is used in finished dosage forms including tablets, enteric-coated formulations, and injectables. Nutraceutical and dietary supplement producers use it as the active ingredient in joint support and cognitive health products. Stable salt forms are preferred over free-base material for processing in these industries. Biotechnology researchers rely on it as a cofactor and reagent in methyltransferase assays and epigenetic research workflows.

Food-grade applications include functional food fortification where methyl donor supplementation is a defined formulation objective. It is supplied as a crystalline powder, typically in stabilized salt form to maintain activity. Material is available in pharmaceutical-grade specifications aligned with USP and BP monograph requirements, as well as research-grade lots for life sciences use. This ensures high purity for sensitive applications.

Bulk quantities are offered for industrial formulation, with smaller pack sizes available for laboratory and development-scale procurement. This flexibility supports both large-scale manufacturing and R&D projects.