S-adenosyl-L-methionine chloride

CAS Number
24346-00-7
EC Number
246-184-8

What is S-adenosyl-L-methionine chloride?

S-adenosyl-L-methionine chloride (CAS 24346-00-7), also known as SAM chloride, is a stabilized salt form of the endogenous methyl donor S-adenosylmethionine.

Where is S-adenosyl-L-methionine chloride used?

  • Pharmaceutical manufacturing: key intermediate
  • Nutraceutical and dietary supplement: active ingredient in joint support and cognitive health products
  • Biotechnology: cofactor and reagent in methyltransferase assays and epigenetic research workflows
  • Functional food fortification where methyl donor supplementation is a defined formulation objective
  • It functions as a methyl group donor in enzymatic synthesis and as an active ingredient in formulations targeting liver health and mood support.

Good to know: Stable salt forms are preferred over free-base material for processing. Pharmaceutical-grade specifications aligned with USP and BP monograph requirements, as well as research-grade lots for life sciences use.

Commercial specifications

  • Pharmaceutical-grade specifications aligned with USP and BP monograph requirements
  • Research-grade lots for life sciences use
  • Bulk quantities for industrial formulation; smaller pack sizes for laboratory and development-scale procurement

Other Names (Synonyms)

S-adenosylmethionine chloride|SAM chloride|B02SK72839|ADEMETIONINE CHLORIDE|(3S)-5'-((3-Amino-3-carboxypropyl)methylsulphonio)-5'-deoxyadenosine chloride|Adenosine, 5′-[(3-amino-3-carboxypropyl)methylsulfonio]-5′-deoxy-, chloride|Methionine, S-(5-deoxyadenos-5-yl)-, chloride, L-|Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, chloride

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What are the physical properties of S-adenosyl-L-methionine chloride?

Color Off-White to Dark Yellow
Form Solid

Which trade and regulatory codes apply to S-adenosyl-L-methionine chloride?

WGK (Germany) 1
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