Methyl nicotinate
Description
Methyl nicotinate (CAS 93-60-7), also known commercially as Heat Spray in topical applications, is the methyl ester of nicotinic acid used across pharmaceutical synthesis, flavor formulation, and cosmetic actives.
FEMA 3709 status confirms its recognized standing as a flavoring agent in food and beverage applications. In pharmaceutical manufacturing, it serves as a key intermediate in the synthesis of niacin derivatives.
It is utilized in active pharmaceutical ingredients targeting metabolic pathways. Food and beverage formulators use it as a flavoring agent, contributing roasted, meaty, or savory nuance to processed food products.
In personal care and cosmetic formulations, its vasodilatory effect on skin microcirculation makes it a functional active in warming creams, sports massage products, and topical heat-effect preparations.
Fragrance and flavor houses also source it as a building block for heterocyclic aroma compounds in tobacco and savory flavor profiles. Methyl nicotinate is supplied as a white to off-white crystalline solid.
Standard commercial grades include technical, food-grade, and pharmaceutical-grade material meeting USP or BP specifications. This ensures high purity for sensitive industrial and medical applications.
Packaging typically ranges from kilogram quantities up to bulk drum supply depending on grade and application requirements. We ensure consistent quality and supply chain reliability for all global shipments.
Physical Properties
| Melting Point | 42.5 °C |
| Boiling Point | 102-104 °C @ Press: 15 Torr |
| Density | 1.2528 (rough estimate) |
| Flash Point | 204 °F |
| Appearance | white to brownish crystals or crystalline powder |
| Color | White to brownish |
| Odor | at 10.00 % in dipropylene glycol. warm herbal tobacco |
| Form | Crystals or Crystalline Powder |
| Water Solubility | NEGLIGIBLE |
| Vapor Pressure | 0.4 hPa (25 °C) |
| Refractive Index | 1.5323 (estimate) |
| Log P | 0.68 at 25℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29333999 |
| WGK (Germany) | 3 |
Documentation
Other Names
Nicotinic acid, methyl ester|Methyl 3-pyridinecarboxylate|Heat spray|3-pyridinecarboxylic acid methyl ester|3-(Methoxycarbonyl)pyridine|3-(Carbomethoxy)pyridine|methyl pyridine-3-carboxylate|Nicometh
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