Methyl nicotinate
CAS Number
93-60-7
EC Number
202-261-8
FEMA Number
FEMA 3709
What is Methyl nicotinate?
Methyl nicotinate (CAS 93-60-7), also known commercially as Heat Spray in topical applications, is the methyl ester of nicotinic acid. FEMA 3709.
Where is Methyl nicotinate used?
- Pharmaceutical manufacturing: intermediate in synthesis of niacin derivatives
- Active pharmaceutical ingredients targeting metabolic pathways
- Food and beverage: flavoring agent with roasted, meaty or savory nuance in processed foods
- Personal care and cosmetics: vasodilatory active in warming creams, sports massage products and topical heat-effect preparations
- Fragrance and flavor houses use it as a building block for heterocyclic aroma compounds in tobacco and savory profiles.
Commercial specifications
- Packaging from kilogram quantities up to bulk drum supply
Other Names (Synonyms)
Nicotinic acid, methyl ester|Methyl 3-pyridinecarboxylate|Heat spray|3-pyridinecarboxylic acid methyl ester|3-(Methoxycarbonyl)pyridine|3-(Carbomethoxy)pyridine|methyl pyridine-3-carboxylate|Nicometh
What are the physical properties of Methyl nicotinate?
Melting Point 42.5 °C
Boiling Point 102-104 °C @ Press: 15 Torr
Density 1.2528 (rough estimate)
Flash Point 204 °F
Appearance white to brownish crystals or crystalline powder
Color White to brownish
Odor at 10.00 % in dipropylene glycol. warm herbal tobacco
Form Crystals or Crystalline Powder
Water Solubility NEGLIGIBLE
Vapor Pressure 0.4 hPa (25 °C)
Refractive Index 1.5323 (estimate)
Log P 0.68 at 25℃
How is Methyl nicotinate classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary Statements
P264 Wash … thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P321 Specific treatment (see … on this label).
P264+P265 Wash … thoroughly after handling.
Which trade and regulatory codes apply to Methyl nicotinate?
HS Code 29333999
WGK (Germany) 3