Hexyl nicotinate
CAS Number
23597-82-2
EC Number
245-767-4
What is Hexyl nicotinate?
Hexyl nicotinate (CAS 23597-82-2), also known as nicotinic acid hexyl ester, is an ester of nicotinic acid used as a penetration enhancer and carrier in topical formulations.
Where is Hexyl nicotinate used?
- Topical pharmaceuticals: warming or flushing sensation in muscle rub and sports recovery creams and gels
- Cosmetics: anti-cellulite creams and body contouring products where skin redness and microcirculation are endpoints
- Carrier and penetration enhancer improving transdermal delivery of co-formulated actives
- Pharmaceutical intermediates: building block for nicotinic acid derivatives and related heterocyclic compounds
- It promotes localized vasodilation at the skin surface.
Commercial specifications
- Purity typically 98% or higher, confirmed by GC analysis
- Packaging from small laboratory quantities to bulk drums
Other Names (Synonyms)
nicotinic acid hexyl ester|3-pyridinecarboxylic acid hexyl ester|Hexyl 3-pyridinecarboxylate|BN07PB44IV|HYGROPLEX HHG|Nicotherm
What are the physical properties of Hexyl nicotinate?
Boiling Point 140 °C @ Press: 5.0 Torr
Density 1.0133 g/cm³ @ Temp: 25 °C
Color Colorless to Almost colorless
Form clear liquid
Water Solubility 0.17g/L(32 ºC)
Refractive Index 1.4880 to 1.4920
Log P 3.510
How is Hexyl nicotinate classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
Which trade and regulatory codes apply to Hexyl nicotinate?
HS Code 29333990