Methylparaben

CAS Number
99-76-3
EC Number
202-785-7
Chemical Formula
C8H8O3
Molecular Weight
152.15 g/mol
E Number
E218
FEMA Number
FEMA 2710

Description

Methylparaben (CAS 99-76-3), also known as Tegosept M, is a synthetic antimicrobial preservative used across pharmaceutical, cosmetic, and food manufacturing. It inhibits the growth of bacteria, yeast, and mold in finished formulations. This chemical extends product shelf life at low use concentrations. In pharmaceutical manufacturing, it preserves oral suspensions, topical creams, and injectable preparations where microbial contamination control is a regulatory requirement.

Personal care producers rely on it to protect lotions, shampoos, and makeup products from spoilage throughout their shelf life. Food and beverage manufacturers apply it under FEMA 2710 designation to protect goods. It is commonly used in processed goods, beverages, and flavoring systems. It also functions as a UV stabilizer in certain formulations, protecting active ingredients from photodegradation during storage and transport.

Methylparaben is supplied as a white crystalline powder. Standard grades include USP, BP, Ph. Eur., and FCC, covering pharmaceutical, cosmetic, and food-grade procurement requirements for global supply chains. Technical grade is available for industrial preservation applications where compendial certification is not required. This versatile preservative remains a staple for ensuring product safety and stability across multiple industries.

Other Names (Synonyms)

Tegosept M|p-methoxycarbonylphenol|P-Hydroxybenzoic methyl ester|P-Hydroxybenzoic acid, methyl ester|p-carbomethoxyphenol|Nipagin M|nipagin|Methyl-p-hydroxybenzoate

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 131 °C
Boiling Point 265 °C
Density 1.383 g/cm³ (crystalline) @ Temp: 25 °C; Press: 750 Torr
Flash Point 280°C
Appearance white crystalline powder
Color White to almost white
Odor odorless or faint char. odor, sl. burning taste
Form Crystalline Powder
Water Solubility Slightly soluble in water.
Vapor Pressure 0.000005 hPa (20 °C)
Refractive Index 1.4447 (estimate)
pH 5.8 (H2O, 20°C) (saturated solution)
Log P 1.98 at 20℃

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.

Trade & Regulatory

HS Code 29182930
UN Number 2769
WGK (Germany) 1
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