Isobutylparaben

CAS Number
4247-02-3
EC Number
224-208-8

What is Isobutylparaben?

Isobutylparaben (CAS 4247-02-3), also known as isobutyl 4-hydroxybenzoate, is a paraben-series preservative used in food, pharmaceutical, and cosmetic manufacturing.

Where is Isobutylparaben used?

  • Cosmetics and personal care: preservative in creams, lotions, and emulsions where longer oil-phase compatibility is required compared to shorter-chain parabens
  • Pharmaceuticals: topical preparations, oral suspensions, and semi-solid dosage forms to prevent microbial contamination during storage
  • Food: antimicrobial agent in certain processed food products where regulatory frameworks permit paraben use
  • It also appears as an intermediate in the synthesis of more complex paraben esters.

Commercial specifications

  • Food-grade and pharmaceutical-grade material, the latter typically conforming to USP specifications
  • May also conform to Ph. Eur. standards
  • Packaging in kilogram-scale quantities for laboratory and formulation use, and larger bulk formats for industrial production

Other Names (Synonyms)

Isobutyl 4-hydroxybenzoate|Isobutyl p-hydroxybenzoate|Isobutyl parahydroxybenzoate|Benzoic acid, 4-hydroxy-, 2-methylpropyl ester|Benzoic acid, p-hydroxy-, isobutyl ester|2-Methylpropyl p-hydroxybenzoate

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What are the physical properties of Isobutylparaben?

Melting Point 74-77 °C
Boiling Point 302.3±15.0 °C(Predicted)
Density 1.105±0.06 g/cm3(Predicted)
Color White
Form neat
Water Solubility Insoluble in water.
Vapor Pressure 0.001Pa at 20℃
Log P 3.43 at 23℃

How is Isobutylparaben classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H318 Causes serious eye damage

Precautionary Statements

P264 Wash … thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P321 Specific treatment (see … on this label).

Which trade and regulatory codes apply to Isobutylparaben?

HS Code 29182900
UN Number 3077
ADR Class 9
Packing Group III
Storage Class 13 - Non Combustible Solids
WGK (Germany) 2
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