Biotin
Description
Biotin (CAS 58-85-5), commonly known as Vitamin B7 or Vitamin H, is a water-soluble B-complex vitamin that functions as a coenzyme in carboxylation reactions critical to metabolism.
In commercial supply, it is sourced as a pure active ingredient for use across nutritional, pharmaceutical, cosmetic, and biotechnology manufacturing sectors worldwide.
In dietary supplements and functional foods, it is incorporated into capsules, tablets, and fortified products targeting hair, skin, and nail health claims for consumers.
Pharmaceutical manufacturers use it as an active ingredient in prescription and OTC formulations, requiring documented purity and traceability to meet strict regulatory standards.
In personal care, it is added to shampoos, conditioners, and topical serums where label claims around hair and nail strength drive significant consumer demand in the market.
Biotechnology applications rely on its strong affinity for streptavidin and avidin, making it a standard reagent in assay development, diagnostic kits, and cell culture media.
The product is supplied as a white to off-white crystalline powder. Standard grades include USP, BP, and Ph. Eur. for pharmaceutical and nutraceutical applications.
Feed-grade material is available for animal nutrition. Pre-diluted blends at 1% or 2% concentrations in carriers such as dextrose or starch are also available for easier handling.
Physical Properties
| Melting Point | 232 °C (decomp) |
| Boiling Point | 573.6±35.0 °C(Predicted) |
| Density | 1.42 g/cm³ |
| Appearance | White powder |
| Color | White crystalline powder or fine long needles |
| Form | powder |
| Water Solubility | Soluble in hot water, dimethyl sulfoxide, alcohol and benzene. |
| Refractive Index | 90.5 ° (C=2, 0.1mol/L NaOH) |
| pH | 4.5 (0.1g/l, H2O) |
| Log P | 0.861 (est) |
Trade & Regulatory
| HS Code | 29362930 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 1 |
Documentation
Other Names
5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoic acid|5-[(1R,5S,6S)-3-oxo-7-thia-2,4-diazabicyclo[3.3.0]oct-6-yl]pentanoic acid|5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid|5-(2-Oxohexahydro-1H-thieno[3,4-D]imidazol-4-yl)pentanoate|1swr|1swn|1swk|(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acid
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