Vitamin A Retinol

CAS Number
68-26-8
EC Number
200-683-7
Chemical Formula
C20H30O
Molecular Weight
286.5 g/mol

Description

Retinol (CAS 68-26-8), also marketed as Vitamin A1, is the bioavailable alcohol form of Vitamin A used across cosmetic, nutritional, and pharmaceutical manufacturing. It functions as a cell-renewal active in topical formulations. In cosmetics, retinol is the primary active in anti-aging serums, night creams, and treatment moisturizers, where it drives skin cell turnover at concentrations typically ranging from 0.01% to 1%.

Nutritional supplement manufacturers incorporate it into softgel capsules, multivitamin tablets, and fortified powders to meet established dietary reference values. Food producers use it to fortify dairy products. It is also utilized in infant formula and cooking oils, restoring vitamin content lost during processing. Pharmaceutical-grade retinol enters topical drug formulations and compounded preparations targeting dermatological indications.

Retinol is supplied as a crystalline powder or stabilized oil solution, with oil-based forms common for easier handling and formulation incorporation. Standard grades include USP, BP, and Ph. Eur. These grades support pharmaceutical and nutraceutical compliance requirements. Food-grade material meeting FCC specifications is available for fortification applications and various industrial processes.

Encapsulated or beadlet forms are offered to improve stability during processing and shelf life. These specialized formats ensure the active ingredient remains potent throughout the manufacturing cycle.

Other Names (Synonyms)

Retinol|Vitamin A1|trans-Retinol|Chocola A|beta-Retinol|b-Retinol|ATROL|all-trans-vitamin A alcohol|all-trans-retinyl alcohol

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 62-64 °C
Boiling Point 137-138 °C @ Press: 1 x 10-6 Torr
Density 0.9933 (rough estimate)
Flash Point -26 °C
Appearance Yellow-Orange Powder
Color yellow to orange
Form crystalline
Water Solubility Practically insoluble inwaterorglycerol; soluble in absolute alcohol,methanol,℃hloroform, ether, fats and oils.
Refractive Index 1.641
pH 6.5-7.5 (20°C, 100g/L in H2O)
Log P 5.680

Documentation

Safety & Handling Learn More

Danger
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 Harmful if swallowed
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H360 May damage fertility or the unborn child
H413 May cause long lasting harmful effects to aquatic life

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Trade & Regulatory

HS Code 29362100
UN Number 1208
ADR Class 3
Packing Group II
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 3
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