Vitamins
REACH
Vitamin A Retinol
CAS Number
68-26-8
EC Number
200-683-7
What is Vitamin A Retinol?
Retinol (CAS 68-26-8), also marketed as Vitamin A1, is the bioavailable alcohol form of Vitamin A.
Where is Vitamin A Retinol used?
- Cosmetics: primary active in anti-aging serums, night creams and treatment moisturizers
- Topical formulations: cell-renewal active
- Nutritional supplements: softgel capsules, multivitamin tablets and fortified powders
- Food: fortification of dairy products, infant formula and cooking oils
- Pharmaceutical-grade retinol enters topical drug formulations and compounded preparations for dermatological indications.
Commercial specifications
- Skin cell turnover at concentrations typically ranging from 0.01% to 1%
- Grades: USP, BP, Ph. Eur., FCC
- Encapsulated or beadlet forms for stability during processing and shelf life
Other Names (Synonyms)
Retinol|Vitamin A1|trans-Retinol|Chocola A|beta-Retinol|b-Retinol|ATROL|all-trans-vitamin A alcohol|all-trans-retinyl alcohol
What are the physical properties of Vitamin A Retinol?
Melting Point 62-64 °C
Boiling Point 137-138 °C @ Press: 1 x 10-6 Torr
Density 0.9933 (rough estimate)
Flash Point -26 °C
Appearance Yellow-Orange Powder
Color yellow to orange
Form crystalline
Water Solubility Practically insoluble inwaterorglycerol; soluble in absolute alcohol,methanol,℃hloroform, ether, fats and oils.
Refractive Index 1.641
pH 6.5-7.5 (20°C, 100g/L in H2O)
Log P 5.680
How is Vitamin A Retinol classified and handled safely? Learn More
Danger
GHS07· Irritant GHS08· Health Hazard
Hazard Statements
H302 Harmful if swallowed
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H360 May damage fertility or the unborn child
H413 May cause long lasting harmful effects to aquatic life
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Which trade and regulatory codes apply to Vitamin A Retinol?
HS Code 29362100
UN Number 1208
ADR Class 3
Packing Group II
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
WGK (Germany) 3