Retinyl propionate
Description
Retinyl propionate (CAS 7069-42-3), also known as Retinol propionate, is a vitamin A ester used in cosmetic and pharmaceutical formulations as a stable, skin-active retinoid source.
It delivers retinoid activity with improved oxidative stability compared to free retinol, making it a preferred ingredient for formulators managing shelf-life and efficacy in various products.
In premium skincare formulations, it is incorporated into anti-aging serums, creams, and emulsions where controlled retinoid delivery is required without the irritation profile associated with stronger retinoids.
It is used in over-the-counter cosmetic products targeting skin renewal, tone correction, and texture improvement, where regulatory positioning as a cosmetic ingredient is commercially advantageous.
Pharmaceutical-grade applications include topical preparations where a milder retinoid ester is clinically preferred. Personal care manufacturers also incorporate it into sun care and post-exposure products.
Retinyl propionate is typically supplied as an oil or oily liquid, suitable for direct incorporation into lipid phases of emulsions and anhydrous formulations for diverse manufacturing needs.
It is available in cosmetic and pharmaceutical grades, with specifications aligned to purity requirements for each application segment. Packaging is designed to minimize light and oxygen exposure.
Physical Properties
| Boiling Point | 453.7±14.0 °C(Predicted) |
| Density | 0.963±0.06 g/cm3(Predicted) |
| Flash Point | 128 °C |
| Color | Pale Yellow to Yellow |
| Form | Oil |
| Vapor Pressure | 0-0Pa at 20-96.2℃ |
| Log P | 9.12 at 25℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 1 |
Documentation
Other Names
Retinol propionate|Retinol, propanoate|32JK994WMC|VITAMIN A PROPIONATE 2.5 MIO IU/G|RefChem:879488|Retinol, 15-propanoate|Retinol, propionate, all-trans-
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