Tocopheryl acetate
Description
Tocopheryl acetate (CAS 58-95-7), also known as Vitamin E acetate, is the esterified, shelf-stable form of Vitamin E used across food, pharmaceutical, and cosmetic manufacturing.
Unlike free tocopherol, the acetate ester resists oxidation during processing and storage, making it the preferred supply form for formulators requiring consistent potency and long-term stability.
It functions as both a nutritional supplement ingredient and an antioxidant stabilizer in finished products. In dietary supplements, it delivers Vitamin E activity in softgel capsules and fortified oils.
Pharmaceutical manufacturers incorporate it into injectable formulations and oral dosage forms requiring a standardized, pharmacopeial-grade active. It is also used in vitamin blends for clinical applications.
In personal care, it protects emulsions and skin-conditioning products from lipid oxidation. Food producers use it to fortify infant formula and cereal products to meet regulatory enrichment requirements.
Tocopheryl acetate is supplied as a clear, viscous oil, with natural-source and synthetic versions available. Recognized specifications include USP, BP, Ph. Eur., and food-grade FCC.
Concentration variants such as 50% and 70% dilutions in carrier oils are also standard for premix and feed applications. These formats ensure easy handling and precise dosing during large-scale production.
Physical Properties
| Melting Point | -27.5 °C |
| Boiling Point | 200-210 °C @ Press: 0.1 Torr |
| Density | 0.9533 g/cm³ @ Temp: 21.34 °C |
| Flash Point | >230 °F |
| Appearance | off-white crystalline solid |
| Color | yellow |
| Odor | cryst., odorless |
| Form | oil or semi-solid |
| Water Solubility | <0.1 g/100 mL at 17 ºC |
| Refractive Index | n 20/D 1.496(lit.) |
| Log P | 12.260 (est) |
Trade & Regulatory
| HS Code | 29362800 |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 1 |
Documentation
Other Names
Vitamin E acetate, D-|Tocopherol acetate|RRR-alpha-tocopheryl acetate|D-alpha-Tocopheryl acetate|D-alpha-Tocopherol acetate|D-alpha tocoferil acetate|alpha-tocopheryl acetate, D-|(+)-alfa-tocopherol acetate
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