Vitamin C Ascorbyl Palmitate

CAS Number
137-66-6
EC Number
205-305-4
E Number
E304

What is Vitamin C Ascorbyl Palmitate?

Ascorbyl palmitate (CAS 137-66-6), also known by its EU food additive designation E304i, is a fat-soluble ester of vitamin C used commercially as an antioxidant and stabilizer.

Where is Vitamin C Ascorbyl Palmitate used?

  • Food: added to oils, fats and fat-containing products such as margarines, baked goods and infant formula to retard rancidity
  • Pharmaceutical: protection of oxidation-sensitive actives in lipid-based drug delivery systems and soft gels
  • Cosmetics: antioxidant preservative and skin-conditioning agent in creams, serums and sunscreens
  • It also serves as a co-emulsifier in lipid dispersions.

Good to know: Unlike water-soluble ascorbic acid, its lipophilic character makes it effective at protecting oils, fats and lipid-based systems from oxidative degradation.

Commercial specifications

  • Cosmetic grade typically at or above 98% purity
  • Food-grade meets FCC specifications
  • USP and Ph. Eur. grades for pharmaceutical applications

Other Names (Synonyms)

Ascorbyl palmitate|L-ascorbic acid 6-hexadecanoate|E304i|6-O-palmitoylascorbic acid|L-Ascorbyl 6-palmitate|L-Ascorbic acid 6-palmitate|Ascorbyl monopalmitate|Ascorbic palmitate|L-Ascorbyl palmitate

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What are the physical properties of Vitamin C Ascorbyl Palmitate?

Melting Point 116 °C
Boiling Point 512.7±50.0 °C(Predicted)
Density 1.150±0.06 g/cm3(Predicted)
Color White to Pale Gray
Odor wh. or yel.-wh. powd., citrus odor
Form neat
Refractive Index 22.5 ° (C=1, EtOH)
Log P 6.5 at 30℃ and pH1.9

How is Vitamin C Ascorbyl Palmitate classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H319 Causes serious eye irritation
H412 Harmful to aquatic life with long lasting effects

Precautionary Statements

P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Which trade and regulatory codes apply to Vitamin C Ascorbyl Palmitate?

HS Code 29362700
Storage Class 11 - Combustible Solids
WGK (Germany) 1
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