Ethyl ascorbic acid

CAS Number
86404-04-8
EC Number
617-849-3
Chemical Formula
C8H12O6
Molecular Weight
204.18 g/mol
Abbreviation
VCE

Description

Ethyl ascorbic acid (CAS 86404-04-8), also known as 3-O-Ethyl Ascorbic Acid or VCE, is a stabilized ether derivative of Vitamin C used as a skin-brightening and antioxidant active in cosmetic formulations. Unlike pure ascorbic acid, it maintains stability in aqueous systems while delivering bioavailable Vitamin C to skin tissue. It is a high-demand ingredient among formulators developing advanced skincare actives.

The primary application is in brightening serums and creams, where it targets uneven skin tone and hyperpigmentation in leave-on formulations. It is incorporated into anti-aging products alongside niacinamide or retinol. These formulations deliver antioxidant protection and support collagen synthesis claims. Toners and ampoules in the K-beauty and prestige skincare segments frequently feature it as a lead active at specific concentrations.

Usage levels typically range from 1% to 3% depending on the desired efficacy. Sunscreen formulations also use it as an antioxidant booster to complement UV filter systems for enhanced skin protection. Ethyl ascorbic acid is supplied as a white to off-white crystalline powder. It is available in cosmetic-grade specification, the standard for personal care applications, with purity typically at 98% or above.

Packaging is commonly offered in kilogram quantities up to bulk drum supply to serve both development-scale and commercial production needs. This ensures reliable supply chains for global manufacturers.

Other Names (Synonyms)

(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-ethoxy-4-hydroxy-2H-furan-5-one|3-o-ethyl ascorbic acid|VCE

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 116-117.5 °C
Boiling Point 551.5±50.0 °C(Predicted)
Density 1.46±0.1 g/cm3(Predicted)
Color White to Off-White
Form Solid
Vapor Pressure 0-0Pa at 20-25℃
Log P -0.8--0.64 at 20-25℃ and pH7

Safety & Handling (Learn More)

Warning
GHS07· Irritant

Hazard Statements

H319 Causes serious eye irritation

Precautionary Statements

P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265 Wash … thoroughly after handling.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 2936.27.0000
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

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