SoleChem

Azelaic acid

CAS
123-99-9
EC
204-669-1
Mol. Weight
188.22 g/mol

Description

Azelaic acid (CAS 123-99-9) is a saturated dicarboxylic acid used as a functional building block and active ingredient across cosmetic, polymer, and industrial lubricant applications.

It is commercially recognized under the pharmaceutical trade names Skinoren and Skinorem, particularly in dermatological product sourcing contexts for various global markets.

In personal care and pharmaceutical formulations, this acid is the active ingredient in topical products targeting acne and hyperpigmentation, where it functions as a pH-regulating and antimicrobial agent.

Polymer manufacturers use it as a monomer to produce polyamides and polyesters with improved flexibility and low-temperature performance, particularly in specialty coatings and adhesives.

In lubricant formulations, azelaic acid esters produced through esterification with branched alcohols serve as synthetic base fluids and plasticizers suited to high-performance and low-temperature applications.

It also acts as a corrosion inhibitor and dispersant additive in metalworking fluids. The material is supplied as a white crystalline powder or granules for easy handling and processing.

Standard commercial grades include technical, cosmetic, and pharmaceutical grades, with the latter meeting USP and Ph. Eur. specifications for high-purity manufacturing requirements.

Purity levels of 98–99%+ are typical for high-specification applications, while technical-grade material is available for polymer and lubricant end uses across the chemical industry.

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Physical Properties

Melting Point 106.5 °C
Boiling Point 225 °C @ Press: 10 Torr
Density 1.251 g/cm³
Flash Point 215 °C
Appearance white to cream solid
Color White to slightly yellow
Form Slightly Crystalline Powder or Flakes
Water Solubility 2.4 g/L (20 ºC)
Vapor Pressure <1 mm Hg ( 20 °C)
Refractive Index 1.4303
pH 3.5 (1g/l, H2O)
Log P 1.57 at 25℃

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary Statements
P264 Wash … thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P321 Specific treatment (see … on this label).
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29171390
Storage Class 11 - Combustible Solids
WGK (Germany) 1

Documentation

Other Names

Skinoren|Skinorem|Polyazelaic anhydride|Nonanedioic acid homopolymer|Nonanedioic acid azelaic acid|Nonanedioic acid|Nonandisäure

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