Disodium azelate

Disodium azelate (CAS 17265-13-3), the disodium salt of azelaic acid, is a water-soluble buffering agent used in personal care and pharmaceutical formulations. It provides pH stabilization in aqueous systems where the free acid form presents solubility challenges.

In topical pharmaceutical formulations, it functions as a buffering component in creams and gels targeting skin conditions where azelaic acid is the active ingredient. This improves the deliverable form's stability profile during long-term storage.

Cosmetic formulators incorporate it into serums and emulsions to maintain target pH ranges while contributing the recognized skin-conditioning benefits associated with the azelate anion. It is highly effective in aqueous-based systems.

It also serves pharmaceutical manufacturers as an intermediate in synthesis workflows requiring a neutralized, salt-form dicarboxylate starting material. This allows for more efficient processing in complex chemical reactions.

Aqueous-based personal care systems, particularly those sensitive to acidic excipients, benefit from its buffering capacity without the low-pH handling concerns of the parent acid. This makes it a versatile choice for modern formulations.

Disodium azelate is typically supplied as a white to off-white powder or crystalline solid. It is available in technical and cosmetic-grade specifications to meet various industrial needs and performance requirements.

Pharmaceutical-grade material is supplied to meet purity requirements aligned with formulation-grade standards. Packaging options generally range from laboratory quantities to bulk orders suited for industrial formulation batches.