Alpha cyclodextrin
CAS Number
10016-20-3
EC Number
233-007-4
Abbreviation
α-CD
What is Alpha cyclodextrin?
Alpha cyclodextrin (CAS 10016-20-3), also known as Alfadex, is a cyclic oligosaccharide derived from starch that forms inclusion complexes with guest molecules.
Where is Alpha cyclodextrin used?
- Pharmaceuticals: encapsulation of poorly soluble APIs to improve bioavailability
- Oral and topical drug formulations: more effective delivery
- Food: stabilisation of flavours and fat-soluble vitamins against oxidation and volatility loss
- Personal care: encapsulation of fragrance compounds and actives, extending scent longevity
- Skin and hair products: controlled release
- Functional food and nutraceuticals: fat absorption management
- It also functions as a dietary fiber ingredient.
Good to know: The pharmaceutical grade conforms to USP, Ph. Eur., and BP monographs. High-purity grades are required for regulated food and drug applications.
Commercial specifications
- Bulk quantities standard for industrial procurement
Other Names (Synonyms)
Alfadex|α-cyclodextrin|(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol|alpha-cyclodextrin|α-CD
What are the physical properties of Alpha cyclodextrin?
Melting Point >278 °C (dec.)(lit.)
Boiling Point 784.04°C (rough estimate)
Density 1.521 g/cm³ (solid)
Appearance White crystalline powder
Color White
Odor Odorless
Form powder
Water Solubility Soluble in water at 1%(w/v)
Refractive Index 1.7500 (estimate)
pH 5.0-8.0 (1% in solution)
Log P -7.77
Which trade and regulatory codes apply to Alpha cyclodextrin?
HS Code 29400090
WGK (Germany) 3