alpha-D-glucose pentaacetate

Alpha-D-glucose pentaacetate (CAS 604-68-2), also known as pentaacetyl-alpha-D-glucose, is a fully acetylated glucose derivative used primarily as a pharmaceutical intermediate and specialty chemical in fine chemical synthesis. It serves as a protected glucose building block, enabling selective glycosylation reactions without the need for additional protection steps. In pharmaceutical manufacturing, it functions as a key starting material for synthesis.

This compound is used for synthesizing nucleoside analogues, glycosylated drug compounds, and other carbohydrate-based active pharmaceutical ingredients. Its well-defined anomeric configuration makes it the preferred precursor for stereoselective glycosylation. This precision is critical to API purity and regulatory compliance. In personal care formulations, it is evaluated as a stabilizing and moisturizing agent where controlled release of glucose moieties supports skin conditioning performance.

Research and specialty chemical producers also use it as a reference standard or reagent-grade intermediate in carbohydrate chemistry workflows. It is supplied as a white to off-white crystalline powder for various uses. It is available in reagent-grade and pharmaceutical-grade specifications to meet the purity requirements of API synthesis and GMP-compliant manufacturing environments. Packaging typically ranges from laboratory-scale quantities up to bulk orders.