SoleChem

alpha-D-glucose pentaacetate

CAS
604-68-2
EC
210-073-2
Mol. Weight
390.34 g/mol

Description

Alpha-D-glucose pentaacetate (CAS 604-68-2), also known as pentaacetyl-alpha-D-glucose, is a fully acetylated glucose derivative used primarily as a pharmaceutical intermediate and specialty chemical in fine chemical synthesis.

It serves as a protected glucose building block, enabling selective glycosylation reactions without the need for additional protection steps. In pharmaceutical manufacturing, it functions as a key starting material for synthesis.

This compound is used for synthesizing nucleoside analogues, glycosylated drug compounds, and other carbohydrate-based active pharmaceutical ingredients. Its well-defined anomeric configuration makes it the preferred precursor for stereoselective glycosylation.

This precision is critical to API purity and regulatory compliance. In personal care formulations, it is evaluated as a stabilizing and moisturizing agent where controlled release of glucose moieties supports skin conditioning performance.

Research and specialty chemical producers also use it as a reference standard or reagent-grade intermediate in carbohydrate chemistry workflows. It is supplied as a white to off-white crystalline powder for various uses.

It is available in reagent-grade and pharmaceutical-grade specifications to meet the purity requirements of API synthesis and GMP-compliant manufacturing environments. Packaging typically ranges from laboratory-scale quantities up to bulk orders.

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Physical Properties

Melting Point 113.3 °C
Boiling Point ~0.115 °C (approx) @ Press: 3 x 10-4 Torr
Density 1.3984 (rough estimate)
Appearance white to light yellow crystal powde
Color White to off-white
Odor at 100.00 %. odorless
Form Powder
Water Solubility < 5 G/L (25 ºC)
Vapor Pressure 0-0Pa at 20-50℃
Refractive Index 105.5 ° (C=1.5, MeOH)
Log P 1.87 at 25℃ and pH5.7

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H302 Harmful if swallowed
H317 May cause an allergic skin reaction
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P501 Dispose of contents/container in accordance with local regulations.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P333+P317 Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.

Trade & Regulatory

HS Code 29224210
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

alpha-D-Glucopyranose, pentaacetate|Pentaacetyl-alpha-D-glucose|1,2,3,4,6-Penta-O-acetyl-alpha-D-glucopyranose|Penta-O-acetyl-alpha-D-glucopyranose|1CS424NS93|α-D-Glucopyranose, 1,2,3,4,6-pentaacetate|Glucopyranose, pentaacetate, α-D-|α-D-Glucopyranose, pentaacetate

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