Pantolactone
CAS Number
79-50-5
EC Number
201-210-7
What is Pantolactone?
Pantolactone (CAS 79-50-5), also known as DL-Pantolactone, is a cyclic lactone intermediate. It is used in pharmaceutical synthesis, cosmetic formulation and food processing.
Where is Pantolactone used?
- Pharmaceutical manufacturing: precursor in the synthesis of pantothenic acid and coenzyme A derivatives
- Cosmetics: moisture-retention in skin care serums and creams
- Hair care: conditioning treatments that improve texture
- Food and flavour: stabilising nutrient premixes and fortified products
- Fine chemicals: resolved or racemic chiral synthon for asymmetric synthesis
- It functions as a chiral building block and stabilising agent.
Good to know: Controlled stereochemistry drives sourcing decisions in medical applications. Both racemic (DL) and optically active forms exist.
Commercial specifications
- Purity grades from technical to high-purity pharmaceutical-grade, often meeting USP or FCC standards
- Packaging from kilogram quantities to bulk drums
Other Names (Synonyms)
RefChem:390767|DL-Pantolactone|3-hydroxy-4,4-dimethyldihydrofuran-2(3H)-one|3-hydroxy-4,4-dimethyloxolan-2-one|DL-Pantoyl Lactone|2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-|Butyric acid, α,γ-dihydroxy-β,β-dimethyl-, γ-lactone|Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
What are the physical properties of Pantolactone?
Melting Point 48-49 °C
Boiling Point 64 °C @ Press: 0.15 Torr
Density 1.165±0.06 g/cm3(Predicted)
Flash Point 122°C
Color Colourless Gel to White to Off-White
Form Solid
Water Solubility H2O: 1g/10 mL, clear, colorless to almost colorless
How is Pantolactone classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H319 Causes serious eye irritation
Precautionary Statements
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265 Wash … thoroughly after handling.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Which trade and regulatory codes apply to Pantolactone?
HS Code 29322090
WGK (Germany) 3