SoleChem

Pantolactone

CAS
79-50-5
EC
201-210-7
Mol. Weight
130.14 g/mol

Description

Pantolactone (CAS 79-50-5), also supplied as DL-Pantolactone, is a cyclic lactone intermediate used across pharmaceutical synthesis, cosmetic formulation, and food processing. It functions primarily as a chiral building block and stabilizing agent.

This chemical is essential in the production of pantothenic acid (Vitamin B5) and related compounds. In pharmaceutical manufacturing, it serves as a key precursor in the synthesis of pantothenic acid and coenzyme A derivatives.

Controlled stereochemistry drives sourcing decisions for this material in medical applications. Cosmetic formulators incorporate it into skin care products for its moisture-retention properties, supporting hydration in serums and creams.

It is also utilized in hair conditioning treatments to improve texture and health. In food and flavor applications, it contributes stabilizing functionality to nutrient premixes and various fortified products.

Research and fine chemical producers source it as a resolved or racemic chiral synthon for asymmetric synthesis programs. The material is available as a white crystalline powder or solid for industrial use.

It is supplied in both racemic (DL) and optically active forms to meet specific needs. Purity grades range from technical to high-purity pharmaceutical-grade material, often meeting USP or FCC standards.

Packaging typically ranges from kilogram quantities to bulk drums, depending on application requirements. This versatility ensures that both laboratory and large-scale manufacturing needs are met efficiently.

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Physical Properties

Melting Point 48-49 °C
Boiling Point 64 °C @ Press: 0.15 Torr
Density 1.165±0.06 g/cm3(Predicted)
Flash Point 122°C
Color Colourless Gel to White to Off-White
Form Solid
Water Solubility H2O: 1g/10 mL, clear, colorless to almost colorless

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H319 Causes serious eye irritation
Precautionary Statements
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265 Wash … thoroughly after handling.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29322090
WGK (Germany) 3

Documentation

Other Names

RefChem:390767|DL-Pantolactone|3-hydroxy-4,4-dimethyldihydrofuran-2(3H)-one|3-hydroxy-4,4-dimethyloxolan-2-one|DL-Pantoyl Lactone|2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-|Butyric acid, α,γ-dihydroxy-β,β-dimethyl-, γ-lactone|Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone

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