Pentaethylene glycol

CAS Number
4792-15-8
EC Number
225-341-4
Abbreviation
PEG-5

What is Pentaethylene glycol?

Pentaethylene glycol (CAS 4792-15-8), also abbreviated as PEG-5, is a mid-chain polyethylene glycol diol used as a humectant, plasticizer, and solvent.

Where is Pentaethylene glycol used?

  • Pharmaceutical formulations: solvent and carrier for active ingredients in topical and semi-solid dosage forms
  • Polymer and plastics: plasticizer that improves flexibility and processability in films and coatings
  • Textile and leather processing: softening agent and humectant that maintains substrate moisture balance
  • Metalworking fluids: lubricant component and carrier in water-miscible cutting and grinding fluid systems
  • Its defined five-unit ethylene oxide chain makes it a well-characterized building block for formulators requiring a specific molecular weight fraction.

Good to know: Specification alignment with USP or Ph. Eur. PEG monographs should be confirmed; consult the supplier for regulated applications.

Commercial specifications

  • Drum and IBC quantities
  • Technical and pharmaceutical-grade specifications
  • Buyers verify defined purity thresholds for regulatory requirements

Other Names (Synonyms)

HO[CH2CH2O]5H|3,6,9,12-Tetraoxatetradecane-1,14-diol|RefChem:171360|HO-PEG5-OH|2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethanol|1,2-Bis[2-(2-hydroxyethoxy)ethoxy]ethane|3,6,9,12-Tetraoxatetradecan-1,14-diol|PEG-5

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What are the physical properties of Pentaethylene glycol?

Melting Point 187 °C
Boiling Point 174-176 °C @ Press: 0.14 Torr
Density 1.1424 g/cm³ (liquid) @ Temp: 50 °C; Press: 7.13 x 10⁵ Torr
Flash Point >230 °F
Appearance colourless liquid
Color Clear colorless to yellow
Form Liquid
Water Solubility Miscible with water.
Refractive Index n 20/D 1.462(lit.)

How is Pentaethylene glycol classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to Pentaethylene glycol?

HS Code 29094990
Storage Class 10 - Combustible liquids
WGK (Germany) 3
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